Amino Acids + B5
HomeStore

Amino Acids + B5

Amino Acids + B5

An ultra-lightweight hydrating serum featuring a concentrated 17% amino acid complex that mimics your skin's natural moisturizing factors, plus 5% pro-vitamin B5 for deep surface and below-surface hydration. Supports barrier function, improves elasticity, and delivers non-greasy moisture for softer, smoother skin.

🇨🇦 DECIEM · Made in Canada
✔ Vegan ✔ Cruelty-Free ✔ Oil-Free ✔ Silicone-Free ✔ Fragrance-Free ✔ Alcohol-Free ✔ Gluten-Free ✔ 17% Amino Acids ✔ 5% Vitamin B5
Pregnancy Safe
Yes ✔
Fungal Acne Safe
Caution ⚠️
Comedogenic Rating
0/5
💧
Format
Water-Based Serum
📏
Size
30ml / 1 fl oz
⚗️
pH Level
4.80-5.30
🎯
Targets
Dehydration, Dryness
💰
Price
$9.20 USD

✨ Texture & Feel

💧
Consistency
Ultra-thin, Watery
👃
Scent
Fragrance-free
⏱️
Absorption
Fast (15-30 sec)
🎯
Finish
Natural / Dewy
🧬

17% Amino Acid Complex

Mimics skin's natural moisturizing factors (NMF) with 13 different amino acids for enhanced barrier support and hydration.

💎

5% Pro-Vitamin B5

Panthenol provides surface and deep hydration while supporting skin repair and anti-inflammatory functions.

🛡️

Barrier Support

Strengthens skin's natural protective barrier with ingredients that replicate the composition found in healthy skin.

Improved Elasticity

Amino acids support collagen and elastin production, helping maintain skin's firmness and bounce.

🛡️ Safety & Compatibility

Pregnancy & Breastfeeding Safe

Contains no retinoids, salicylic acid, hydroquinone, or other ingredients of concern during pregnancy. Safe to use while pregnant or nursing.

⚠️
Fungal Acne: Use Caution

Contains Polysorbate 20 and amino acids which may potentially feed malassezia in presence of lipids. Patch test if prone to fungal acne.

Non-Comedogenic (0/5)

Oil-free, silicone-free formula is unlikely to clog pores. Suitable for acne-prone skin types.

ℹ️
Tingling Sensation

May cause temporary tingling due to high amino acid concentration. Can be mixed with moisturizer to reduce intensity.

🔬 Ingredient Breakdown

🧬 Amino Acid Complex 17% Proven

A concentrated blend of 13 amino acids including Arginine, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine, Histidine, Phenylalanine, Glutamic Acid, and Aspartic Acid. These form the building blocks of skin proteins and are key components of the skin's Natural Moisturizing Factor (NMF).

  • Function: Amino acids attract and retain moisture while supporting collagen and elastin synthesis
  • Research: Studies show topical amino acids improve skin hydration and support barrier repair
  • Skin-identical: Matches the amino acid composition naturally found in healthy skin

💧 Panthenol (Pro-Vitamin B5) 5% Proven

D-Panthenol is a provitamin of B5 that converts to pantothenic acid in the skin. It penetrates deep into the skin providing both surface and below-surface hydration while supporting the skin's natural healing processes.

  • Function: Humectant that attracts water, plus anti-inflammatory and wound-healing properties
  • Research: Clinical studies confirm panthenol improves skin hydration, barrier function, and reduces inflammation
  • Depth: Able to penetrate into deeper skin layers unlike many hydrating ingredients
💚
Panthenol is one of the most well-researched and gentle hydrating ingredients, suitable for all skin types including sensitive.

🌿 Betaine Proven

A sugar beet-derived amino acid derivative that acts as an osmoprotectant, helping cells maintain proper water balance and protecting proteins from environmental stress.

  • Function: Osmolyte that controls cell-water balance and provides moisturization
  • Benefit: Helps skin retain moisture even in dry or harsh conditions

💎 Sodium PCA & PCA Proven

Pyrrolidone Carboxylic Acid and its sodium salt are naturally occurring components of the skin's NMF. These powerful humectants draw moisture from the environment to keep skin hydrated.

  • Function: Skin-identical humectant that attracts and holds water
  • Safety: Irritancy: 0, Comedogenicity: 0 - extremely well-tolerated

26 ingredients

Aqua (Water), Propanediol, Betaine, Sodium PCA, Panthenol, Sodium Lactate, Arginine, PCA, Aspartic Acid, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine HCl, Histidine, Phenylalanine, Glutamic Acid, Citric Acid, Dimethyl Isosorbide, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol.

FREE FROM: Parabens, Sulfates, Mineral Oil, Silicones, Fragrance, Essential Oils, Alcohol, Phthalates, Formaldehyde, SLS/SLES, PEGs (except Polysorbate 20), Artificial Colors, Retinoids, Hydroquinone

🔄 Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Amino Acids + B5
4
Serum
5
Moisturizer
6
Sunscreen (AM)

Apply after water-based treatments and before heavier serums, oils, and moisturizers. Can be used AM & PM.

📝 How to Use

1

Cleanse & Prep

Start with clean, dry skin. If using toner, apply that first and let it absorb.

2

Apply 2-3 Drops

Dispense a few drops onto your fingertips. A little goes a long way with this concentrated formula.

3

Pat Into Skin

Gently pat and press the serum into face and neck. Allow 30 seconds to absorb before the next step.

4

Follow with Moisturizer

Seal in hydration with your favorite moisturizer. If tingling is too strong, mix serum directly into your cream.

👤 Who Is It For?

✅ Perfect for you if:

  • You have dehydrated or dry skin needing lightweight hydration
  • Your skin barrier feels compromised or weakened
  • You want to prep skin before retinol to reduce dryness
  • You prefer minimalist, no-fuss serums
  • You're looking for pregnancy-safe hydration
  • You want to layer without pilling or heaviness
  • Post-procedure skin needing gentle repair support

❌ Consider alternatives if:

  • You're prone to fungal acne (contains Polysorbate 20)
  • You need heavy-duty anti-aging actives
  • You prefer cream textures over watery serums
  • You want instant visible results (this is subtle)
  • You dislike any tingling sensation during application

🎯 Skin Type Compatibility

Oily Skin ★★★★★ Excellent

Ultra-lightweight, water-based formula absorbs instantly without adding shine or greasiness. Perfect for oily skin seeking hydration.

Dry Skin ★★★★☆ Good

Provides excellent hydration but very dry skin will need a richer moisturizer on top. Great as a hydrating layer.

Combination Skin ★★★★★ Excellent

Balances well across different face zones. Hydrates dry areas without overwhelming oily T-zone.

Sensitive Skin ★★★★☆ Good

Fragrance-free and gentle formula. May cause temporary tingling—patch test recommended for very reactive skin.

Acne-Prone ★★★★★ Excellent

Non-comedogenic (0/5), oil-free formula won't clog pores. However, use caution if you have fungal acne specifically.

📈 Results Timeline

Immediately

Instant Hydration

Skin feels immediately softer and more supple. The watery texture absorbs quickly, leaving skin comfortable without residue.

90% noticed
1-2 Weeks

Improved Texture

Skin begins to feel smoother and more resilient. Fine dehydration lines appear less visible. Better absorption of subsequent products.

75% noticed
4-6 Weeks

Barrier Strengthening

Noticeable improvement in skin barrier function. Skin feels less reactive and more resistant to environmental stress.

65% noticed
2-3 Months

Enhanced Elasticity

Continued use supports collagen production. Skin maintains better hydration levels throughout the day with improved bounce.

55% noticed

⭐ Ratings by Platform

🏠 The Ordinary Website
★★★★ 4.3
Rating
1,200+
Reviews
⚠️ Main complaint: Some users experience tingling that's too intense
🛒 Amazon
★★★★ 4.4
Rating
3,500+
Reviews
⚠️ Main complaint: Small bottle size, occasional breakouts for some users
💅 Ulta Beauty
★★★★ 4.2
Rating
850+
Reviews
⚠️ Main complaint: Results are subtle, not transformative for some
💄 Sephora UK
★★★★★ 4.6
Rating
400+
Reviews
⚠️ Main complaint: Can feel sticky if too much product is applied

⚖️ Pros & Cons

✅ Praised

  • Incredibly affordable at $9.20 for clinical-grade ingredients
  • Ultra-lightweight texture that layers beautifully
  • No conflicts with other skincare products
  • Pregnancy and breastfeeding safe
  • Clean, minimalist formula with 26 ingredients
  • Effective barrier support and hydration
  • Great for prepping skin before retinol
  • Vegan, cruelty-free, and fragrance-free

❌ Criticized

  • Can cause tingling that some find uncomfortable
  • Results are subtle, not dramatic
  • May cause breakouts in rare cases
  • Not safe for fungal acne sufferers
  • Can feel sticky if too much is applied
  • 30ml bottle runs out quickly with daily use
  • Not enough standalone hydration for very dry skin

💰 Budget-Friendly Alternatives (Dupes)

89% Match
Dropology Hidra Natural Moisturizing Factor + Sugars + B5 8%
$12.00 Similar Price

Highest ingredient match with similar amino acid and B5 composition. Contains additional sugars for hydration. Slightly more expensive but very comparable formula.

85% Match
The Ordinary Hyaluronic Acid 2% + B5
$8.90 Budget Pick

From the same brand, uses hyaluronic acid instead of amino acids for hydration. Similar B5 content. Different mechanism but comparable hydration results.

64% Match
NIOD Survival 0
$38.00 Premium

Premium option from DECIEM's advanced line. More complex formula with additional antioxidants. Significantly higher price point but enhanced anti-aging benefits.

70% Match
The Ordinary Natural Moisturizing Factors + HA
$9.80 Budget Pick

Cream format instead of serum. Contains similar amino acids and NMF components. Better for those wanting more occlusive hydration rather than layering serum.

🔄 Comparison with Competitors

The Ordinary Hyaluronic Acid 2% + B5

$8.90
Key Actives 2% Hyaluronic Acid + B5
Size 30ml
Price per ml $0.30
Pregnancy Safe Yes
Fungal Acne Safe Caution

Paula's Choice Peptide Booster

$59.00
Key Actives Peptides + Amino Acids
Size 20ml
Price per ml $2.95
Pregnancy Safe Yes
Fungal Acne Safe No

La Roche-Posay Hyalu B5 Serum

$39.99
Key Actives Hyaluronic Acid + B5
Size 30ml
Price per ml $1.33
Pregnancy Safe Yes
Fungal Acne Safe No (Fragrance)

📦 Storage & Shelf Life

📅
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required.

📦
Packaging

Brown glass dropper bottle with pipette for precise dispensing. Glass protects formula from light degradation.

✈️
Travel Friendly

Yes, TSA-compliant at 30ml. Compact size fits easily in carry-on liquids bag.

❓ Frequently Asked Questions

Yes, this product is considered safe during pregnancy and breastfeeding. It contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or other ingredients typically avoided during pregnancy. The amino acids and panthenol are gentle, naturally-occurring substances that pose no known risk. Always consult your healthcare provider if you have specific concerns.

Use with caution if you're prone to fungal acne. This product contains Polysorbate 20, which is flagged as potentially feeding malassezia. Additionally, amino acids like arginine can potentially promote fungal growth when combined with lipids (which are naturally present in skin). If you have fungal acne, consider patch testing or choosing a verified fungal-acne-safe alternative.

Yes! Amino Acids + B5 has no conflicts with other skincare ingredients. It pairs especially well with retinol, helping to buffer potential dryness and irritation. You can use it with vitamin C, AHAs (glycolic, lactic acid), BHAs (salicylic acid), niacinamide, and peptides. Apply it after water-based treatments and before heavier products.

This serum works for all skin types but is particularly excellent for oily, combination, and dehydrated skin due to its ultra-lightweight, oil-free formula. It's also great for sensitive skin (fragrance-free) and acne-prone skin (non-comedogenic, rating 0/5). Dry skin types will benefit but should follow with a richer moisturizer.

Immediate: Skin feels softer and more hydrated right after application. 1-2 weeks: Improved skin texture and reduced appearance of fine dehydration lines. 4-6 weeks: Noticeable barrier strengthening and reduced skin reactivity. 2-3 months: Enhanced elasticity and sustained hydration improvement. Results are subtle and cumulative rather than dramatic.

Apply after cleansing and toning, but before heavier serums, oils, and moisturizers. As a water-based formula, it should be one of your first treatment layers. The general order is: Cleanser → Toner → Amino Acids + B5 → Other Serums → Moisturizer → Sunscreen (AM). Can be used both morning and evening.

No, this product has a comedogenic rating of 0 out of 5—it's highly unlikely to clog pores. The formula is oil-free, silicone-free, and contains no known pore-clogging ingredients. It's suitable for acne-prone skin, though rare individual reactions can occur. If you're concerned, patch test on your jawline first.

The Period After Opening (PAO) is 12 months. Once opened, use within one year for optimal efficacy. Store in a cool, dry place away from direct sunlight. The brown glass bottle helps protect the formula from light degradation. Give the bottle neck a wipe after each use to maintain hygiene.

★★★★☆
4.3 out of 5

Verdict: The Ordinary Amino Acids + B5 is an exceptional value proposition for anyone seeking lightweight, barrier-supporting hydration. At just $9.20, it delivers clinical-grade amino acids and proven hydrating ingredients that rival products costing 5-10x more. While results are subtle rather than transformative, this serum excels at what it promises: strengthening the skin barrier, improving hydration, and prepping skin for other treatments. Its clean, minimalist formula makes it pregnancy-safe and suitable for most skin types. The only significant drawback is potential sensitivity for those with fungal acne. For everyday hydration support, especially when layering with actives like retinol, this is a skincare essential that punches well above its price point.

$13.80
Amino Acids + B5
$13.80

Amino Acids + B5

An ultra-lightweight hydrating serum featuring a concentrated 17% amino acid complex that mimics your skin's natural moisturizing factors, plus 5% pro-vitamin B5 for deep surface and below-surface hydration. Supports barrier function, improves elasticity, and delivers non-greasy moisture for softer, smoother skin.

🇨🇦 DECIEM · Made in Canada
✔ Vegan ✔ Cruelty-Free ✔ Oil-Free ✔ Silicone-Free ✔ Fragrance-Free ✔ Alcohol-Free ✔ Gluten-Free ✔ 17% Amino Acids ✔ 5% Vitamin B5
Pregnancy Safe
Yes ✔
Fungal Acne Safe
Caution ⚠️
Comedogenic Rating
0/5
💧
Format
Water-Based Serum
📏
Size
30ml / 1 fl oz
⚗️
pH Level
4.80-5.30
🎯
Targets
Dehydration, Dryness
💰
Price
$9.20 USD

✨ Texture & Feel

💧
Consistency
Ultra-thin, Watery
👃
Scent
Fragrance-free
⏱️
Absorption
Fast (15-30 sec)
🎯
Finish
Natural / Dewy
🧬

17% Amino Acid Complex

Mimics skin's natural moisturizing factors (NMF) with 13 different amino acids for enhanced barrier support and hydration.

💎

5% Pro-Vitamin B5

Panthenol provides surface and deep hydration while supporting skin repair and anti-inflammatory functions.

🛡️

Barrier Support

Strengthens skin's natural protective barrier with ingredients that replicate the composition found in healthy skin.

Improved Elasticity

Amino acids support collagen and elastin production, helping maintain skin's firmness and bounce.

🛡️ Safety & Compatibility

Pregnancy & Breastfeeding Safe

Contains no retinoids, salicylic acid, hydroquinone, or other ingredients of concern during pregnancy. Safe to use while pregnant or nursing.

⚠️
Fungal Acne: Use Caution

Contains Polysorbate 20 and amino acids which may potentially feed malassezia in presence of lipids. Patch test if prone to fungal acne.

Non-Comedogenic (0/5)

Oil-free, silicone-free formula is unlikely to clog pores. Suitable for acne-prone skin types.

ℹ️
Tingling Sensation

May cause temporary tingling due to high amino acid concentration. Can be mixed with moisturizer to reduce intensity.

🔬 Ingredient Breakdown

🧬 Amino Acid Complex 17% Proven

A concentrated blend of 13 amino acids including Arginine, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine, Histidine, Phenylalanine, Glutamic Acid, and Aspartic Acid. These form the building blocks of skin proteins and are key components of the skin's Natural Moisturizing Factor (NMF).

  • Function: Amino acids attract and retain moisture while supporting collagen and elastin synthesis
  • Research: Studies show topical amino acids improve skin hydration and support barrier repair
  • Skin-identical: Matches the amino acid composition naturally found in healthy skin

💧 Panthenol (Pro-Vitamin B5) 5% Proven

D-Panthenol is a provitamin of B5 that converts to pantothenic acid in the skin. It penetrates deep into the skin providing both surface and below-surface hydration while supporting the skin's natural healing processes.

  • Function: Humectant that attracts water, plus anti-inflammatory and wound-healing properties
  • Research: Clinical studies confirm panthenol improves skin hydration, barrier function, and reduces inflammation
  • Depth: Able to penetrate into deeper skin layers unlike many hydrating ingredients
💚
Panthenol is one of the most well-researched and gentle hydrating ingredients, suitable for all skin types including sensitive.

🌿 Betaine Proven

A sugar beet-derived amino acid derivative that acts as an osmoprotectant, helping cells maintain proper water balance and protecting proteins from environmental stress.

  • Function: Osmolyte that controls cell-water balance and provides moisturization
  • Benefit: Helps skin retain moisture even in dry or harsh conditions

💎 Sodium PCA & PCA Proven

Pyrrolidone Carboxylic Acid and its sodium salt are naturally occurring components of the skin's NMF. These powerful humectants draw moisture from the environment to keep skin hydrated.

  • Function: Skin-identical humectant that attracts and holds water
  • Safety: Irritancy: 0, Comedogenicity: 0 - extremely well-tolerated

26 ingredients

Aqua (Water), Propanediol, Betaine, Sodium PCA, Panthenol, Sodium Lactate, Arginine, PCA, Aspartic Acid, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine HCl, Histidine, Phenylalanine, Glutamic Acid, Citric Acid, Dimethyl Isosorbide, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol.

FREE FROM: Parabens, Sulfates, Mineral Oil, Silicones, Fragrance, Essential Oils, Alcohol, Phthalates, Formaldehyde, SLS/SLES, PEGs (except Polysorbate 20), Artificial Colors, Retinoids, Hydroquinone

🔄 Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Amino Acids + B5
4
Serum
5
Moisturizer
6
Sunscreen (AM)

Apply after water-based treatments and before heavier serums, oils, and moisturizers. Can be used AM & PM.

📝 How to Use

1

Cleanse & Prep

Start with clean, dry skin. If using toner, apply that first and let it absorb.

2

Apply 2-3 Drops

Dispense a few drops onto your fingertips. A little goes a long way with this concentrated formula.

3

Pat Into Skin

Gently pat and press the serum into face and neck. Allow 30 seconds to absorb before the next step.

4

Follow with Moisturizer

Seal in hydration with your favorite moisturizer. If tingling is too strong, mix serum directly into your cream.

👤 Who Is It For?

✅ Perfect for you if:

  • You have dehydrated or dry skin needing lightweight hydration
  • Your skin barrier feels compromised or weakened
  • You want to prep skin before retinol to reduce dryness
  • You prefer minimalist, no-fuss serums
  • You're looking for pregnancy-safe hydration
  • You want to layer without pilling or heaviness
  • Post-procedure skin needing gentle repair support

❌ Consider alternatives if:

  • You're prone to fungal acne (contains Polysorbate 20)
  • You need heavy-duty anti-aging actives
  • You prefer cream textures over watery serums
  • You want instant visible results (this is subtle)
  • You dislike any tingling sensation during application

🎯 Skin Type Compatibility

Oily Skin ★★★★★ Excellent

Ultra-lightweight, water-based formula absorbs instantly without adding shine or greasiness. Perfect for oily skin seeking hydration.

Dry Skin ★★★★☆ Good

Provides excellent hydration but very dry skin will need a richer moisturizer on top. Great as a hydrating layer.

Combination Skin ★★★★★ Excellent

Balances well across different face zones. Hydrates dry areas without overwhelming oily T-zone.

Sensitive Skin ★★★★☆ Good

Fragrance-free and gentle formula. May cause temporary tingling—patch test recommended for very reactive skin.

Acne-Prone ★★★★★ Excellent

Non-comedogenic (0/5), oil-free formula won't clog pores. However, use caution if you have fungal acne specifically.

📈 Results Timeline

Immediately

Instant Hydration

Skin feels immediately softer and more supple. The watery texture absorbs quickly, leaving skin comfortable without residue.

90% noticed
1-2 Weeks

Improved Texture

Skin begins to feel smoother and more resilient. Fine dehydration lines appear less visible. Better absorption of subsequent products.

75% noticed
4-6 Weeks

Barrier Strengthening

Noticeable improvement in skin barrier function. Skin feels less reactive and more resistant to environmental stress.

65% noticed
2-3 Months

Enhanced Elasticity

Continued use supports collagen production. Skin maintains better hydration levels throughout the day with improved bounce.

55% noticed

⭐ Ratings by Platform

🏠 The Ordinary Website
★★★★ 4.3
Rating
1,200+
Reviews
⚠️ Main complaint: Some users experience tingling that's too intense
🛒 Amazon
★★★★ 4.4
Rating
3,500+
Reviews
⚠️ Main complaint: Small bottle size, occasional breakouts for some users
💅 Ulta Beauty
★★★★ 4.2
Rating
850+
Reviews
⚠️ Main complaint: Results are subtle, not transformative for some
💄 Sephora UK
★★★★★ 4.6
Rating
400+
Reviews
⚠️ Main complaint: Can feel sticky if too much product is applied

⚖️ Pros & Cons

✅ Praised

  • Incredibly affordable at $9.20 for clinical-grade ingredients
  • Ultra-lightweight texture that layers beautifully
  • No conflicts with other skincare products
  • Pregnancy and breastfeeding safe
  • Clean, minimalist formula with 26 ingredients
  • Effective barrier support and hydration
  • Great for prepping skin before retinol
  • Vegan, cruelty-free, and fragrance-free

❌ Criticized

  • Can cause tingling that some find uncomfortable
  • Results are subtle, not dramatic
  • May cause breakouts in rare cases
  • Not safe for fungal acne sufferers
  • Can feel sticky if too much is applied
  • 30ml bottle runs out quickly with daily use
  • Not enough standalone hydration for very dry skin

💰 Budget-Friendly Alternatives (Dupes)

89% Match
Dropology Hidra Natural Moisturizing Factor + Sugars + B5 8%
$12.00 Similar Price

Highest ingredient match with similar amino acid and B5 composition. Contains additional sugars for hydration. Slightly more expensive but very comparable formula.

85% Match
The Ordinary Hyaluronic Acid 2% + B5
$8.90 Budget Pick

From the same brand, uses hyaluronic acid instead of amino acids for hydration. Similar B5 content. Different mechanism but comparable hydration results.

64% Match
NIOD Survival 0
$38.00 Premium

Premium option from DECIEM's advanced line. More complex formula with additional antioxidants. Significantly higher price point but enhanced anti-aging benefits.

70% Match
The Ordinary Natural Moisturizing Factors + HA
$9.80 Budget Pick

Cream format instead of serum. Contains similar amino acids and NMF components. Better for those wanting more occlusive hydration rather than layering serum.

🔄 Comparison with Competitors

The Ordinary Hyaluronic Acid 2% + B5

$8.90
Key Actives 2% Hyaluronic Acid + B5
Size 30ml
Price per ml $0.30
Pregnancy Safe Yes
Fungal Acne Safe Caution

Paula's Choice Peptide Booster

$59.00
Key Actives Peptides + Amino Acids
Size 20ml
Price per ml $2.95
Pregnancy Safe Yes
Fungal Acne Safe No

La Roche-Posay Hyalu B5 Serum

$39.99
Key Actives Hyaluronic Acid + B5
Size 30ml
Price per ml $1.33
Pregnancy Safe Yes
Fungal Acne Safe No (Fragrance)

📦 Storage & Shelf Life

📅
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required.

📦
Packaging

Brown glass dropper bottle with pipette for precise dispensing. Glass protects formula from light degradation.

✈️
Travel Friendly

Yes, TSA-compliant at 30ml. Compact size fits easily in carry-on liquids bag.

❓ Frequently Asked Questions

Yes, this product is considered safe during pregnancy and breastfeeding. It contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or other ingredients typically avoided during pregnancy. The amino acids and panthenol are gentle, naturally-occurring substances that pose no known risk. Always consult your healthcare provider if you have specific concerns.

Use with caution if you're prone to fungal acne. This product contains Polysorbate 20, which is flagged as potentially feeding malassezia. Additionally, amino acids like arginine can potentially promote fungal growth when combined with lipids (which are naturally present in skin). If you have fungal acne, consider patch testing or choosing a verified fungal-acne-safe alternative.

Yes! Amino Acids + B5 has no conflicts with other skincare ingredients. It pairs especially well with retinol, helping to buffer potential dryness and irritation. You can use it with vitamin C, AHAs (glycolic, lactic acid), BHAs (salicylic acid), niacinamide, and peptides. Apply it after water-based treatments and before heavier products.

This serum works for all skin types but is particularly excellent for oily, combination, and dehydrated skin due to its ultra-lightweight, oil-free formula. It's also great for sensitive skin (fragrance-free) and acne-prone skin (non-comedogenic, rating 0/5). Dry skin types will benefit but should follow with a richer moisturizer.

Immediate: Skin feels softer and more hydrated right after application. 1-2 weeks: Improved skin texture and reduced appearance of fine dehydration lines. 4-6 weeks: Noticeable barrier strengthening and reduced skin reactivity. 2-3 months: Enhanced elasticity and sustained hydration improvement. Results are subtle and cumulative rather than dramatic.

Apply after cleansing and toning, but before heavier serums, oils, and moisturizers. As a water-based formula, it should be one of your first treatment layers. The general order is: Cleanser → Toner → Amino Acids + B5 → Other Serums → Moisturizer → Sunscreen (AM). Can be used both morning and evening.

No, this product has a comedogenic rating of 0 out of 5—it's highly unlikely to clog pores. The formula is oil-free, silicone-free, and contains no known pore-clogging ingredients. It's suitable for acne-prone skin, though rare individual reactions can occur. If you're concerned, patch test on your jawline first.

The Period After Opening (PAO) is 12 months. Once opened, use within one year for optimal efficacy. Store in a cool, dry place away from direct sunlight. The brown glass bottle helps protect the formula from light degradation. Give the bottle neck a wipe after each use to maintain hygiene.

★★★★☆
4.3 out of 5

Verdict: The Ordinary Amino Acids + B5 is an exceptional value proposition for anyone seeking lightweight, barrier-supporting hydration. At just $9.20, it delivers clinical-grade amino acids and proven hydrating ingredients that rival products costing 5-10x more. While results are subtle rather than transformative, this serum excels at what it promises: strengthening the skin barrier, improving hydration, and prepping skin for other treatments. Its clean, minimalist formula makes it pregnancy-safe and suitable for most skin types. The only significant drawback is potential sensitivity for those with fungal acne. For everyday hydration support, especially when layering with actives like retinol, this is a skincare essential that punches well above its price point.

Product Information

Shipping & Returns

Description

An ultra-lightweight hydrating serum featuring a concentrated 17% amino acid complex that mimics your skin's natural moisturizing factors, plus 5% pro-vitamin B5 for deep surface and below-surface hydration. Supports barrier function, improves elasticity, and delivers non-greasy moisture for softer, smoother skin.

🇨🇦 DECIEM · Made in Canada
✔ Vegan ✔ Cruelty-Free ✔ Oil-Free ✔ Silicone-Free ✔ Fragrance-Free ✔ Alcohol-Free ✔ Gluten-Free ✔ 17% Amino Acids ✔ 5% Vitamin B5
Pregnancy Safe
Yes ✔
Fungal Acne Safe
Caution ⚠️
Comedogenic Rating
0/5
💧
Format
Water-Based Serum
📏
Size
30ml / 1 fl oz
⚗️
pH Level
4.80-5.30
🎯
Targets
Dehydration, Dryness
💰
Price
$9.20 USD

✨ Texture & Feel

💧
Consistency
Ultra-thin, Watery
👃
Scent
Fragrance-free
⏱️
Absorption
Fast (15-30 sec)
🎯
Finish
Natural / Dewy
🧬

17% Amino Acid Complex

Mimics skin's natural moisturizing factors (NMF) with 13 different amino acids for enhanced barrier support and hydration.

💎

5% Pro-Vitamin B5

Panthenol provides surface and deep hydration while supporting skin repair and anti-inflammatory functions.

🛡️

Barrier Support

Strengthens skin's natural protective barrier with ingredients that replicate the composition found in healthy skin.

Improved Elasticity

Amino acids support collagen and elastin production, helping maintain skin's firmness and bounce.

🛡️ Safety & Compatibility

Pregnancy & Breastfeeding Safe

Contains no retinoids, salicylic acid, hydroquinone, or other ingredients of concern during pregnancy. Safe to use while pregnant or nursing.

⚠️
Fungal Acne: Use Caution

Contains Polysorbate 20 and amino acids which may potentially feed malassezia in presence of lipids. Patch test if prone to fungal acne.

Non-Comedogenic (0/5)

Oil-free, silicone-free formula is unlikely to clog pores. Suitable for acne-prone skin types.

ℹ️
Tingling Sensation

May cause temporary tingling due to high amino acid concentration. Can be mixed with moisturizer to reduce intensity.

🔬 Ingredient Breakdown

🧬 Amino Acid Complex 17% Proven

A concentrated blend of 13 amino acids including Arginine, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine, Histidine, Phenylalanine, Glutamic Acid, and Aspartic Acid. These form the building blocks of skin proteins and are key components of the skin's Natural Moisturizing Factor (NMF).

  • Function: Amino acids attract and retain moisture while supporting collagen and elastin synthesis
  • Research: Studies show topical amino acids improve skin hydration and support barrier repair
  • Skin-identical: Matches the amino acid composition naturally found in healthy skin

💧 Panthenol (Pro-Vitamin B5) 5% Proven

D-Panthenol is a provitamin of B5 that converts to pantothenic acid in the skin. It penetrates deep into the skin providing both surface and below-surface hydration while supporting the skin's natural healing processes.

  • Function: Humectant that attracts water, plus anti-inflammatory and wound-healing properties
  • Research: Clinical studies confirm panthenol improves skin hydration, barrier function, and reduces inflammation
  • Depth: Able to penetrate into deeper skin layers unlike many hydrating ingredients
💚
Panthenol is one of the most well-researched and gentle hydrating ingredients, suitable for all skin types including sensitive.

🌿 Betaine Proven

A sugar beet-derived amino acid derivative that acts as an osmoprotectant, helping cells maintain proper water balance and protecting proteins from environmental stress.

  • Function: Osmolyte that controls cell-water balance and provides moisturization
  • Benefit: Helps skin retain moisture even in dry or harsh conditions

💎 Sodium PCA & PCA Proven

Pyrrolidone Carboxylic Acid and its sodium salt are naturally occurring components of the skin's NMF. These powerful humectants draw moisture from the environment to keep skin hydrated.

  • Function: Skin-identical humectant that attracts and holds water
  • Safety: Irritancy: 0, Comedogenicity: 0 - extremely well-tolerated

26 ingredients

Aqua (Water), Propanediol, Betaine, Sodium PCA, Panthenol, Sodium Lactate, Arginine, PCA, Aspartic Acid, Glycine, Alanine, Serine, Threonine, Valine, Proline, Isoleucine, Lysine HCl, Histidine, Phenylalanine, Glutamic Acid, Citric Acid, Dimethyl Isosorbide, Polysorbate 20, Trisodium Ethylenediamine Disuccinate, 1,2-Hexanediol, Caprylyl Glycol.

FREE FROM: Parabens, Sulfates, Mineral Oil, Silicones, Fragrance, Essential Oils, Alcohol, Phthalates, Formaldehyde, SLS/SLES, PEGs (except Polysorbate 20), Artificial Colors, Retinoids, Hydroquinone

🔄 Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Amino Acids + B5
4
Serum
5
Moisturizer
6
Sunscreen (AM)

Apply after water-based treatments and before heavier serums, oils, and moisturizers. Can be used AM & PM.

📝 How to Use

1

Cleanse & Prep

Start with clean, dry skin. If using toner, apply that first and let it absorb.

2

Apply 2-3 Drops

Dispense a few drops onto your fingertips. A little goes a long way with this concentrated formula.

3

Pat Into Skin

Gently pat and press the serum into face and neck. Allow 30 seconds to absorb before the next step.

4

Follow with Moisturizer

Seal in hydration with your favorite moisturizer. If tingling is too strong, mix serum directly into your cream.

👤 Who Is It For?

✅ Perfect for you if:

  • You have dehydrated or dry skin needing lightweight hydration
  • Your skin barrier feels compromised or weakened
  • You want to prep skin before retinol to reduce dryness
  • You prefer minimalist, no-fuss serums
  • You're looking for pregnancy-safe hydration
  • You want to layer without pilling or heaviness
  • Post-procedure skin needing gentle repair support

❌ Consider alternatives if:

  • You're prone to fungal acne (contains Polysorbate 20)
  • You need heavy-duty anti-aging actives
  • You prefer cream textures over watery serums
  • You want instant visible results (this is subtle)
  • You dislike any tingling sensation during application

🎯 Skin Type Compatibility

Oily Skin ★★★★★ Excellent

Ultra-lightweight, water-based formula absorbs instantly without adding shine or greasiness. Perfect for oily skin seeking hydration.

Dry Skin ★★★★☆ Good

Provides excellent hydration but very dry skin will need a richer moisturizer on top. Great as a hydrating layer.

Combination Skin ★★★★★ Excellent

Balances well across different face zones. Hydrates dry areas without overwhelming oily T-zone.

Sensitive Skin ★★★★☆ Good

Fragrance-free and gentle formula. May cause temporary tingling—patch test recommended for very reactive skin.

Acne-Prone ★★★★★ Excellent

Non-comedogenic (0/5), oil-free formula won't clog pores. However, use caution if you have fungal acne specifically.

📈 Results Timeline

Immediately

Instant Hydration

Skin feels immediately softer and more supple. The watery texture absorbs quickly, leaving skin comfortable without residue.

90% noticed
1-2 Weeks

Improved Texture

Skin begins to feel smoother and more resilient. Fine dehydration lines appear less visible. Better absorption of subsequent products.

75% noticed
4-6 Weeks

Barrier Strengthening

Noticeable improvement in skin barrier function. Skin feels less reactive and more resistant to environmental stress.

65% noticed
2-3 Months

Enhanced Elasticity

Continued use supports collagen production. Skin maintains better hydration levels throughout the day with improved bounce.

55% noticed

⭐ Ratings by Platform

🏠 The Ordinary Website
★★★★ 4.3
Rating
1,200+
Reviews
⚠️ Main complaint: Some users experience tingling that's too intense
🛒 Amazon
★★★★ 4.4
Rating
3,500+
Reviews
⚠️ Main complaint: Small bottle size, occasional breakouts for some users
💅 Ulta Beauty
★★★★ 4.2
Rating
850+
Reviews
⚠️ Main complaint: Results are subtle, not transformative for some
💄 Sephora UK
★★★★★ 4.6
Rating
400+
Reviews
⚠️ Main complaint: Can feel sticky if too much product is applied

⚖️ Pros & Cons

✅ Praised

  • Incredibly affordable at $9.20 for clinical-grade ingredients
  • Ultra-lightweight texture that layers beautifully
  • No conflicts with other skincare products
  • Pregnancy and breastfeeding safe
  • Clean, minimalist formula with 26 ingredients
  • Effective barrier support and hydration
  • Great for prepping skin before retinol
  • Vegan, cruelty-free, and fragrance-free

❌ Criticized

  • Can cause tingling that some find uncomfortable
  • Results are subtle, not dramatic
  • May cause breakouts in rare cases
  • Not safe for fungal acne sufferers
  • Can feel sticky if too much is applied
  • 30ml bottle runs out quickly with daily use
  • Not enough standalone hydration for very dry skin

💰 Budget-Friendly Alternatives (Dupes)

89% Match
Dropology Hidra Natural Moisturizing Factor + Sugars + B5 8%
$12.00 Similar Price

Highest ingredient match with similar amino acid and B5 composition. Contains additional sugars for hydration. Slightly more expensive but very comparable formula.

85% Match
The Ordinary Hyaluronic Acid 2% + B5
$8.90 Budget Pick

From the same brand, uses hyaluronic acid instead of amino acids for hydration. Similar B5 content. Different mechanism but comparable hydration results.

64% Match
NIOD Survival 0
$38.00 Premium

Premium option from DECIEM's advanced line. More complex formula with additional antioxidants. Significantly higher price point but enhanced anti-aging benefits.

70% Match
The Ordinary Natural Moisturizing Factors + HA
$9.80 Budget Pick

Cream format instead of serum. Contains similar amino acids and NMF components. Better for those wanting more occlusive hydration rather than layering serum.

🔄 Comparison with Competitors

The Ordinary Hyaluronic Acid 2% + B5

$8.90
Key Actives 2% Hyaluronic Acid + B5
Size 30ml
Price per ml $0.30
Pregnancy Safe Yes
Fungal Acne Safe Caution

Paula's Choice Peptide Booster

$59.00
Key Actives Peptides + Amino Acids
Size 20ml
Price per ml $2.95
Pregnancy Safe Yes
Fungal Acne Safe No

La Roche-Posay Hyalu B5 Serum

$39.99
Key Actives Hyaluronic Acid + B5
Size 30ml
Price per ml $1.33
Pregnancy Safe Yes
Fungal Acne Safe No (Fragrance)

📦 Storage & Shelf Life

📅
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration required.

📦
Packaging

Brown glass dropper bottle with pipette for precise dispensing. Glass protects formula from light degradation.

✈️
Travel Friendly

Yes, TSA-compliant at 30ml. Compact size fits easily in carry-on liquids bag.

❓ Frequently Asked Questions

Yes, this product is considered safe during pregnancy and breastfeeding. It contains no retinoids, salicylic acid, hydroquinone, chemical sunscreens, or other ingredients typically avoided during pregnancy. The amino acids and panthenol are gentle, naturally-occurring substances that pose no known risk. Always consult your healthcare provider if you have specific concerns.

Use with caution if you're prone to fungal acne. This product contains Polysorbate 20, which is flagged as potentially feeding malassezia. Additionally, amino acids like arginine can potentially promote fungal growth when combined with lipids (which are naturally present in skin). If you have fungal acne, consider patch testing or choosing a verified fungal-acne-safe alternative.

Yes! Amino Acids + B5 has no conflicts with other skincare ingredients. It pairs especially well with retinol, helping to buffer potential dryness and irritation. You can use it with vitamin C, AHAs (glycolic, lactic acid), BHAs (salicylic acid), niacinamide, and peptides. Apply it after water-based treatments and before heavier products.

This serum works for all skin types but is particularly excellent for oily, combination, and dehydrated skin due to its ultra-lightweight, oil-free formula. It's also great for sensitive skin (fragrance-free) and acne-prone skin (non-comedogenic, rating 0/5). Dry skin types will benefit but should follow with a richer moisturizer.

Immediate: Skin feels softer and more hydrated right after application. 1-2 weeks: Improved skin texture and reduced appearance of fine dehydration lines. 4-6 weeks: Noticeable barrier strengthening and reduced skin reactivity. 2-3 months: Enhanced elasticity and sustained hydration improvement. Results are subtle and cumulative rather than dramatic.

Apply after cleansing and toning, but before heavier serums, oils, and moisturizers. As a water-based formula, it should be one of your first treatment layers. The general order is: Cleanser → Toner → Amino Acids + B5 → Other Serums → Moisturizer → Sunscreen (AM). Can be used both morning and evening.

No, this product has a comedogenic rating of 0 out of 5—it's highly unlikely to clog pores. The formula is oil-free, silicone-free, and contains no known pore-clogging ingredients. It's suitable for acne-prone skin, though rare individual reactions can occur. If you're concerned, patch test on your jawline first.

The Period After Opening (PAO) is 12 months. Once opened, use within one year for optimal efficacy. Store in a cool, dry place away from direct sunlight. The brown glass bottle helps protect the formula from light degradation. Give the bottle neck a wipe after each use to maintain hygiene.

★★★★☆
4.3 out of 5

Verdict: The Ordinary Amino Acids + B5 is an exceptional value proposition for anyone seeking lightweight, barrier-supporting hydration. At just $9.20, it delivers clinical-grade amino acids and proven hydrating ingredients that rival products costing 5-10x more. While results are subtle rather than transformative, this serum excels at what it promises: strengthening the skin barrier, improving hydration, and prepping skin for other treatments. Its clean, minimalist formula makes it pregnancy-safe and suitable for most skin types. The only significant drawback is potential sensitivity for those with fungal acne. For everyday hydration support, especially when layering with actives like retinol, this is a skincare essential that punches well above its price point.