No.1 Pantothenic B5 Active Soothing Serum
A lightweight, fast-absorbing daily serum enriched with micro pantothenic acid (Vitamin B5) that delivers 7-second hydration while controlling excess oil and soothing irritated, acne-prone skin. Clinically proven to reduce breakouts by 62% in just 4 weeks.
โจ Texture & Feel
Micro Pantothenic Acid Technology
Ultra-fine vitamin B5 particles penetrate deeply to regulate sebum production and prevent clogged pores from the inside out.
7-Second Hydration System
Triple hyaluronic acid complex (sodium hyaluronate, hydrolyzed HA, and acetylated HA) delivers instant deep moisture without greasiness.
Soothing Booster 12 Complex
Patented blend featuring dipotassium glycyrrhizate, niacinamide, and sophora root extract for comprehensive anti-inflammatory care.
Barrier Strengthening Formula
Beta-glucan and centella asiatica work together to repair and reinforce the skin barrier while calming irritation and redness.
๐ก๏ธ Safety & Compatibility
No retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe for use during pregnancy and nursing.
Contains Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Jojoba Seed Oil which may feed malassezia yeast. Patch test recommended for FA-prone skin.
Clinically tested and confirmed non-comedogenic. Low comedogenic rating (1/5) means minimal risk of clogging pores.
Free from harsh alcohols, parabens, silicones, sulfates, and artificial fragrances. Enriched with soothing centella and allantoin.
Can be safely used with retinol, vitamin C, AHAs, and BHAs. Apply this serum first for hydration, then follow with actives.
Proven to reduce breakouts by 62.22% and excess oil by 37.41% in 4 weeks of clinical testing on acne-prone subjects.
๐ฌ Ingredient Breakdown
๐งฌ Pantothenic Acid (Vitamin B5) Micro-Particles Proven
The star ingredient that gives this serum its name. Pantothenic acid helps regulate sebum production and reduce inflammation associated with acne breakouts.
- Clinical Evidence: Studies show oral and topical B5 can significantly reduce acne lesions by controlling oil gland activity.
- Mechanism: Supports Coenzyme A synthesis, which is essential for metabolizing fatty acids and reducing sebum overproduction.
- Benefits: Oil control, anti-inflammatory, breakout prevention, skin healing support.
๐ Niacinamide (Vitamin B3) 4-5% Proven
A multi-tasking powerhouse that strengthens the skin barrier, regulates oil production, reduces pore appearance, and fades post-acne marks.
- Clinical Evidence: 4% niacinamide shown to significantly reduce sebum excretion and improve skin barrier function.
- Mechanism: Increases ceramide production, inhibits melanin transfer, and reduces inflammatory cytokines.
- Benefits: Oil control, brightening, pore minimizing, barrier repair, anti-aging.
๐ง Panthenol (Pro-Vitamin B5) 1.5-1.8% Proven
The precursor to pantothenic acid that provides deep hydration while soothing irritated and inflamed skin.
- Clinical Evidence: At 1-2% concentration, effectively improves skin hydration and reduces trans-epidermal water loss.
- Mechanism: Penetrates deep into skin layers, converts to pantothenic acid, and promotes lipid barrier synthesis.
- Benefits: Deep hydration, wound healing, anti-inflammatory, skin barrier support.
๐ Triple Hyaluronic Acid Complex Multi-Weight Proven
Three types of hyaluronic acid (Sodium Hyaluronate, Hydrolyzed HA, Sodium Acetylated Hyaluronate) provide multi-layer hydration.
- Sodium Hyaluronate: Mid-weight molecules for surface hydration and plumping.
- Hydrolyzed HA: Low molecular weight for deep penetration into skin layers.
- Sodium Acetylated HA: Enhanced adhesion for long-lasting moisture retention.
๐ Beta-Glucan Promising
A powerful soothing and hydrating ingredient derived from oats or yeast that calms inflammation and supports skin repair.
- Clinical Evidence: Studies show beta-glucan penetrates the epidermis and stimulates collagen synthesis.
- Benefits: Anti-inflammatory, wound healing, antioxidant, immune support for skin.
๐ฟ Centella Asiatica Extract Proven
The legendary "tiger grass" known for its powerful healing and soothing properties, containing asiaticoside and madecassic acid.
- Clinical Evidence: Extensively studied for wound healing, anti-inflammatory, and collagen synthesis properties.
- Benefits: Calms redness, promotes healing, strengthens skin barrier, antioxidant protection.
55 ingredients
Water, Butylene Glycol, Niacinamide, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sophora Angustifolia Root Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Diethoxyethyl Succinate, Tromethamine, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Betaine, Pantothenic Acid, Trehalose, Ethylhexylglycerin, Glyceryl Oleate, Sodium Phytate, Allantoin, Alpha-Arbutin, Houttuynia Cordata Extract, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Zinc PCA, Melia Azadirachta Leaf Extract, Tocopherol, Glycyrrhiza Uralensis (Licorice) Root Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Centella Asiatica Extract, Sodium Hyaluronate, Citric Acid, Solanum Melongena (Eggplant) Fruit Extract, Beta-Glucan, Ocimum Sanctum Leaf Extract, Hyaluronic Acid, Decyl Glucoside, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Dipotassium Glycyrrhizate, Hydrolyzed Hyaluronic Acid, Simmondsia Chinensis (Jojoba) Seed Oil, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, White Willow Bark Extract, Pinus Densiflora Leaf Extract, Coffea Arabica (Coffee) Seed Extract, Citrus Aurantium Bergamia Leaf Extract, Polyglyceryl-10 Stearate, Sodium Acetylated Hyaluronate, Beta-Sitosterol
๐ Where It Fits in Your Routine
Apply after toner on slightly damp skin. For best results, pair with numbuzin No.1 Pantothenic B5 Active Soothing Cream.
๐ How to Use
Cleanse & Prep
Start with a clean face. Apply your toner and let it partially absorb while skin is still slightly damp.
Dispense
Pump 2-3 drops of serum onto your fingertips. A little goes a long way with this concentrated formula.
Apply & Pat
Gently spread the serum across your face and neck, then pat gently to enhance absorption. Absorbs in 7 seconds.
Layer & Protect
Follow with moisturizer and sunscreen (AM). Can be used morning and night for optimal results.
๐ค Who Is It For?
โ Perfect for you if:
- You have oily or combination skin struggling with excess sebum
- You experience frequent breakouts and want to prevent new acne
- You need lightweight hydration that won't feel greasy
- You have sensitive, irritated, or redness-prone skin
- You want to balance oil production without over-drying
- You're looking for a gentle serum safe for daily use
- You want clinical-strength results in a K-beauty formula
โ Consider alternatives if:
- You have fungal acne (malassezia folliculitis) - contains potential triggers
- You have extremely dry skin needing heavy occlusive moisture
- You want a serum focused primarily on anti-aging or brightening
- You prefer products with a richer, cream-like texture
- You're looking for dramatic exfoliation effects
๐ฏ Skin Type Compatibility
Perfect match! Lightweight gel absorbs instantly without adding shine. Controls sebum production throughout the day.
Balances oily T-zone while providing adequate hydration to drier areas. Won't overwhelm either zone.
Clinically proven 62% reduction in breakouts. Non-comedogenic formula actively prevents new blemishes.
Fragrance-free with soothing centella and allantoin. Patch test recommended for very reactive skin.
Provides hydration but may feel lightweight for very dry skin. Layer with a richer moisturizer on top.
Niacinamide and hyaluronic acid provide anti-aging benefits. Best as part of a comprehensive routine.
๐ Results Timeline
Instant Hydration & Comfort
Skin feels immediately soothed and hydrated. The lightweight texture absorbs quickly without any sticky residue.
95% noticed immediate hydrationOil Control Begins
Noticeable reduction in midday shine and oiliness. Skin starts to feel more balanced throughout the day.
78% noticed less oilinessBreakout Reduction
Clinically proven 62.22% reduction in breakouts. Existing blemishes calm down and fewer new ones appear.
62% reduction in breakoutsClear, Balanced Skin
Significant improvement in overall skin clarity. Pores appear smaller, texture smooths out, and redness calms.
85% reported clearer skinโญ Ratings by Platform
โ๏ธ Pros & Cons
โ Praised
- Clinically proven to reduce breakouts by 62% in 4 weeks
- Ultra-lightweight texture absorbs in 7 seconds
- Effectively controls excess oil without over-drying
- Fragrance-free and gentle on sensitive skin
- Non-comedogenic and won't clog pores
- Works well under makeup without pilling
- Calms redness and inflammation quickly
- Pairs perfectly with the No.1 B5 Cream
โ Criticized
- May not be strong enough for extremely oily skin
- Contains potential fungal acne triggers
- 50ml bottle may run out quickly
- Some users found it slightly drying
- Results require consistent use for 4+ weeks
- Not ideal as a standalone moisturizer for dry skin
๐ฐ Budget-Friendly Alternatives (Dupes)
Similar centella-based soothing formula with panthenol. Slightly thicker texture and focuses more on barrier repair than oil control.
49% centella extract with niacinamide and peptides. More focused on soothing/anti-aging than sebum control. Fungal acne safe option.
French pharmacy option with vitamin B5 and hyaluronic acid. More focused on hydration/anti-aging than acne. Contains fragrance.
Propolis and centella formula for acne-prone skin. Moisturizer rather than serum format. Contains betaine salicylate for gentle exfoliation.
๐ Comparison with Competitors
Numbuzin No.1 B5 Serum (This Product)
$25.00COSRX Pure Fit Cica Serum
$18.00PURITO Centella Unscented Serum
$16.00La Roche-Posay Hyalu B5 Serum
$39.99๐ฆ Storage & Shelf Life
12 months after opening
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Hygienic pump bottle with protective cap to prevent contamination and oxidation
Yes - 50ml is under the 100ml TSA liquid limit for carry-on luggage
โ Frequently Asked Questions
Yes, this serum is considered safe during pregnancy and breastfeeding. It does not contain any ingredients of concern such as retinoids, salicylic acid (in problematic concentrations), hydroquinone, or chemical sunscreen filters. The formula relies on gentle, pregnancy-safe ingredients like panthenol, niacinamide, and hyaluronic acid. However, as with any skincare product, it's always best to consult with your healthcare provider if you have specific concerns.
This serum contains some ingredients that may potentially trigger fungal acne, including Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Simmondsia Chinensis (Jojoba) Seed Oil. If you have malassezia folliculitis, we recommend patch testing first or considering a fungal acne-safe alternative like PURITO Centella Unscented Serum. However, many users with acne-prone skin have reported excellent results, so individual responses may vary.
Yes! This serum is compatible with most active ingredients. Apply this serum first for hydration and soothing, then follow with your retinol, vitamin C, or chemical exfoliants. The panthenol and centella in this formula can actually help buffer potential irritation from stronger actives. For sensitive skin, consider alternating nights between this serum and stronger actives rather than layering them together.
This serum is best suited for oily, combination, and acne-prone skin types. It excels at oil control and breakout prevention while providing lightweight hydration. It also works well for sensitive skin due to its soothing ingredients. However, those with very dry skin may find it insufficient as a standalone hydrating product and should layer with a richer moisturizer. Mature skin can also benefit from the niacinamide and hyaluronic acid content.
You'll notice immediate hydration and comfort from the first use. Oil control benefits typically become apparent within 1-2 weeks of consistent use. For breakout reduction, clinical studies showed a 62.22% decrease in blemishes after 4 weeks of twice-daily application. Maximum benefits for skin clarity and texture are usually seen at 4-8 weeks of continuous use. Consistency is key for achieving the best results.
Apply this serum after cleansing and toning, while your skin is still slightly damp. It should go before thicker treatments, moisturizers, and sunscreen. The order is: Cleanser โ Toner โ This Serum โ Treatment serums (retinol, vitamin C) โ Moisturizer โ Sunscreen (AM). You can use it both morning and evening for best results.
No, this serum is clinically tested and confirmed to be non-comedogenic with a very low comedogenic rating of 1/5. The lightweight gel formula is specifically designed for acne-prone skin and absorbs quickly without leaving any residue that could clog pores. The pantothenic acid and niacinamide actually help regulate sebum production and keep pores clear.
The serum has a Period After Opening (PAO) of 12 months. The hygienic pump bottle helps protect the formula from contamination and oxidation. With twice-daily use (2-3 pumps per application), the 50ml bottle typically lasts 2-3 months. Store in a cool, dry place away from direct sunlight to maintain efficacy throughout the usage period.
Verdict: The Numbuzin No.1 Pantothenic B5 Active Soothing Serum is an excellent choice for oily and acne-prone skin seeking lightweight, effective sebum control. Backed by clinical testing showing 62% reduction in breakouts, it delivers on its promises while remaining gentle enough for sensitive skin. The 7-second absorption, fragrance-free formula, and multi-functional ingredients (pantothenic acid, niacinamide, hyaluronic acid) make it a standout in the K-beauty serum category. The only drawbacks are potential fungal acne triggers and it may not be hydrating enough for very dry skin types. At its price point, it offers impressive value compared to Western alternatives.
No.1 Pantothenic B5 Active Soothing Serum
A lightweight, fast-absorbing daily serum enriched with micro pantothenic acid (Vitamin B5) that delivers 7-second hydration while controlling excess oil and soothing irritated, acne-prone skin. Clinically proven to reduce breakouts by 62% in just 4 weeks.
โจ Texture & Feel
Micro Pantothenic Acid Technology
Ultra-fine vitamin B5 particles penetrate deeply to regulate sebum production and prevent clogged pores from the inside out.
7-Second Hydration System
Triple hyaluronic acid complex (sodium hyaluronate, hydrolyzed HA, and acetylated HA) delivers instant deep moisture without greasiness.
Soothing Booster 12 Complex
Patented blend featuring dipotassium glycyrrhizate, niacinamide, and sophora root extract for comprehensive anti-inflammatory care.
Barrier Strengthening Formula
Beta-glucan and centella asiatica work together to repair and reinforce the skin barrier while calming irritation and redness.
๐ก๏ธ Safety & Compatibility
No retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe for use during pregnancy and nursing.
Contains Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Jojoba Seed Oil which may feed malassezia yeast. Patch test recommended for FA-prone skin.
Clinically tested and confirmed non-comedogenic. Low comedogenic rating (1/5) means minimal risk of clogging pores.
Free from harsh alcohols, parabens, silicones, sulfates, and artificial fragrances. Enriched with soothing centella and allantoin.
Can be safely used with retinol, vitamin C, AHAs, and BHAs. Apply this serum first for hydration, then follow with actives.
Proven to reduce breakouts by 62.22% and excess oil by 37.41% in 4 weeks of clinical testing on acne-prone subjects.
๐ฌ Ingredient Breakdown
๐งฌ Pantothenic Acid (Vitamin B5) Micro-Particles Proven
The star ingredient that gives this serum its name. Pantothenic acid helps regulate sebum production and reduce inflammation associated with acne breakouts.
- Clinical Evidence: Studies show oral and topical B5 can significantly reduce acne lesions by controlling oil gland activity.
- Mechanism: Supports Coenzyme A synthesis, which is essential for metabolizing fatty acids and reducing sebum overproduction.
- Benefits: Oil control, anti-inflammatory, breakout prevention, skin healing support.
๐ Niacinamide (Vitamin B3) 4-5% Proven
A multi-tasking powerhouse that strengthens the skin barrier, regulates oil production, reduces pore appearance, and fades post-acne marks.
- Clinical Evidence: 4% niacinamide shown to significantly reduce sebum excretion and improve skin barrier function.
- Mechanism: Increases ceramide production, inhibits melanin transfer, and reduces inflammatory cytokines.
- Benefits: Oil control, brightening, pore minimizing, barrier repair, anti-aging.
๐ง Panthenol (Pro-Vitamin B5) 1.5-1.8% Proven
The precursor to pantothenic acid that provides deep hydration while soothing irritated and inflamed skin.
- Clinical Evidence: At 1-2% concentration, effectively improves skin hydration and reduces trans-epidermal water loss.
- Mechanism: Penetrates deep into skin layers, converts to pantothenic acid, and promotes lipid barrier synthesis.
- Benefits: Deep hydration, wound healing, anti-inflammatory, skin barrier support.
๐ Triple Hyaluronic Acid Complex Multi-Weight Proven
Three types of hyaluronic acid (Sodium Hyaluronate, Hydrolyzed HA, Sodium Acetylated Hyaluronate) provide multi-layer hydration.
- Sodium Hyaluronate: Mid-weight molecules for surface hydration and plumping.
- Hydrolyzed HA: Low molecular weight for deep penetration into skin layers.
- Sodium Acetylated HA: Enhanced adhesion for long-lasting moisture retention.
๐ Beta-Glucan Promising
A powerful soothing and hydrating ingredient derived from oats or yeast that calms inflammation and supports skin repair.
- Clinical Evidence: Studies show beta-glucan penetrates the epidermis and stimulates collagen synthesis.
- Benefits: Anti-inflammatory, wound healing, antioxidant, immune support for skin.
๐ฟ Centella Asiatica Extract Proven
The legendary "tiger grass" known for its powerful healing and soothing properties, containing asiaticoside and madecassic acid.
- Clinical Evidence: Extensively studied for wound healing, anti-inflammatory, and collagen synthesis properties.
- Benefits: Calms redness, promotes healing, strengthens skin barrier, antioxidant protection.
55 ingredients
Water, Butylene Glycol, Niacinamide, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sophora Angustifolia Root Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Diethoxyethyl Succinate, Tromethamine, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Betaine, Pantothenic Acid, Trehalose, Ethylhexylglycerin, Glyceryl Oleate, Sodium Phytate, Allantoin, Alpha-Arbutin, Houttuynia Cordata Extract, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Zinc PCA, Melia Azadirachta Leaf Extract, Tocopherol, Glycyrrhiza Uralensis (Licorice) Root Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Centella Asiatica Extract, Sodium Hyaluronate, Citric Acid, Solanum Melongena (Eggplant) Fruit Extract, Beta-Glucan, Ocimum Sanctum Leaf Extract, Hyaluronic Acid, Decyl Glucoside, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Dipotassium Glycyrrhizate, Hydrolyzed Hyaluronic Acid, Simmondsia Chinensis (Jojoba) Seed Oil, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, White Willow Bark Extract, Pinus Densiflora Leaf Extract, Coffea Arabica (Coffee) Seed Extract, Citrus Aurantium Bergamia Leaf Extract, Polyglyceryl-10 Stearate, Sodium Acetylated Hyaluronate, Beta-Sitosterol
๐ Where It Fits in Your Routine
Apply after toner on slightly damp skin. For best results, pair with numbuzin No.1 Pantothenic B5 Active Soothing Cream.
๐ How to Use
Cleanse & Prep
Start with a clean face. Apply your toner and let it partially absorb while skin is still slightly damp.
Dispense
Pump 2-3 drops of serum onto your fingertips. A little goes a long way with this concentrated formula.
Apply & Pat
Gently spread the serum across your face and neck, then pat gently to enhance absorption. Absorbs in 7 seconds.
Layer & Protect
Follow with moisturizer and sunscreen (AM). Can be used morning and night for optimal results.
๐ค Who Is It For?
โ Perfect for you if:
- You have oily or combination skin struggling with excess sebum
- You experience frequent breakouts and want to prevent new acne
- You need lightweight hydration that won't feel greasy
- You have sensitive, irritated, or redness-prone skin
- You want to balance oil production without over-drying
- You're looking for a gentle serum safe for daily use
- You want clinical-strength results in a K-beauty formula
โ Consider alternatives if:
- You have fungal acne (malassezia folliculitis) - contains potential triggers
- You have extremely dry skin needing heavy occlusive moisture
- You want a serum focused primarily on anti-aging or brightening
- You prefer products with a richer, cream-like texture
- You're looking for dramatic exfoliation effects
๐ฏ Skin Type Compatibility
Perfect match! Lightweight gel absorbs instantly without adding shine. Controls sebum production throughout the day.
Balances oily T-zone while providing adequate hydration to drier areas. Won't overwhelm either zone.
Clinically proven 62% reduction in breakouts. Non-comedogenic formula actively prevents new blemishes.
Fragrance-free with soothing centella and allantoin. Patch test recommended for very reactive skin.
Provides hydration but may feel lightweight for very dry skin. Layer with a richer moisturizer on top.
Niacinamide and hyaluronic acid provide anti-aging benefits. Best as part of a comprehensive routine.
๐ Results Timeline
Instant Hydration & Comfort
Skin feels immediately soothed and hydrated. The lightweight texture absorbs quickly without any sticky residue.
95% noticed immediate hydrationOil Control Begins
Noticeable reduction in midday shine and oiliness. Skin starts to feel more balanced throughout the day.
78% noticed less oilinessBreakout Reduction
Clinically proven 62.22% reduction in breakouts. Existing blemishes calm down and fewer new ones appear.
62% reduction in breakoutsClear, Balanced Skin
Significant improvement in overall skin clarity. Pores appear smaller, texture smooths out, and redness calms.
85% reported clearer skinโญ Ratings by Platform
โ๏ธ Pros & Cons
โ Praised
- Clinically proven to reduce breakouts by 62% in 4 weeks
- Ultra-lightweight texture absorbs in 7 seconds
- Effectively controls excess oil without over-drying
- Fragrance-free and gentle on sensitive skin
- Non-comedogenic and won't clog pores
- Works well under makeup without pilling
- Calms redness and inflammation quickly
- Pairs perfectly with the No.1 B5 Cream
โ Criticized
- May not be strong enough for extremely oily skin
- Contains potential fungal acne triggers
- 50ml bottle may run out quickly
- Some users found it slightly drying
- Results require consistent use for 4+ weeks
- Not ideal as a standalone moisturizer for dry skin
๐ฐ Budget-Friendly Alternatives (Dupes)
Similar centella-based soothing formula with panthenol. Slightly thicker texture and focuses more on barrier repair than oil control.
49% centella extract with niacinamide and peptides. More focused on soothing/anti-aging than sebum control. Fungal acne safe option.
French pharmacy option with vitamin B5 and hyaluronic acid. More focused on hydration/anti-aging than acne. Contains fragrance.
Propolis and centella formula for acne-prone skin. Moisturizer rather than serum format. Contains betaine salicylate for gentle exfoliation.
๐ Comparison with Competitors
Numbuzin No.1 B5 Serum (This Product)
$25.00COSRX Pure Fit Cica Serum
$18.00PURITO Centella Unscented Serum
$16.00La Roche-Posay Hyalu B5 Serum
$39.99๐ฆ Storage & Shelf Life
12 months after opening
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Hygienic pump bottle with protective cap to prevent contamination and oxidation
Yes - 50ml is under the 100ml TSA liquid limit for carry-on luggage
โ Frequently Asked Questions
Yes, this serum is considered safe during pregnancy and breastfeeding. It does not contain any ingredients of concern such as retinoids, salicylic acid (in problematic concentrations), hydroquinone, or chemical sunscreen filters. The formula relies on gentle, pregnancy-safe ingredients like panthenol, niacinamide, and hyaluronic acid. However, as with any skincare product, it's always best to consult with your healthcare provider if you have specific concerns.
This serum contains some ingredients that may potentially trigger fungal acne, including Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Simmondsia Chinensis (Jojoba) Seed Oil. If you have malassezia folliculitis, we recommend patch testing first or considering a fungal acne-safe alternative like PURITO Centella Unscented Serum. However, many users with acne-prone skin have reported excellent results, so individual responses may vary.
Yes! This serum is compatible with most active ingredients. Apply this serum first for hydration and soothing, then follow with your retinol, vitamin C, or chemical exfoliants. The panthenol and centella in this formula can actually help buffer potential irritation from stronger actives. For sensitive skin, consider alternating nights between this serum and stronger actives rather than layering them together.
This serum is best suited for oily, combination, and acne-prone skin types. It excels at oil control and breakout prevention while providing lightweight hydration. It also works well for sensitive skin due to its soothing ingredients. However, those with very dry skin may find it insufficient as a standalone hydrating product and should layer with a richer moisturizer. Mature skin can also benefit from the niacinamide and hyaluronic acid content.
You'll notice immediate hydration and comfort from the first use. Oil control benefits typically become apparent within 1-2 weeks of consistent use. For breakout reduction, clinical studies showed a 62.22% decrease in blemishes after 4 weeks of twice-daily application. Maximum benefits for skin clarity and texture are usually seen at 4-8 weeks of continuous use. Consistency is key for achieving the best results.
Apply this serum after cleansing and toning, while your skin is still slightly damp. It should go before thicker treatments, moisturizers, and sunscreen. The order is: Cleanser โ Toner โ This Serum โ Treatment serums (retinol, vitamin C) โ Moisturizer โ Sunscreen (AM). You can use it both morning and evening for best results.
No, this serum is clinically tested and confirmed to be non-comedogenic with a very low comedogenic rating of 1/5. The lightweight gel formula is specifically designed for acne-prone skin and absorbs quickly without leaving any residue that could clog pores. The pantothenic acid and niacinamide actually help regulate sebum production and keep pores clear.
The serum has a Period After Opening (PAO) of 12 months. The hygienic pump bottle helps protect the formula from contamination and oxidation. With twice-daily use (2-3 pumps per application), the 50ml bottle typically lasts 2-3 months. Store in a cool, dry place away from direct sunlight to maintain efficacy throughout the usage period.
Verdict: The Numbuzin No.1 Pantothenic B5 Active Soothing Serum is an excellent choice for oily and acne-prone skin seeking lightweight, effective sebum control. Backed by clinical testing showing 62% reduction in breakouts, it delivers on its promises while remaining gentle enough for sensitive skin. The 7-second absorption, fragrance-free formula, and multi-functional ingredients (pantothenic acid, niacinamide, hyaluronic acid) make it a standout in the K-beauty serum category. The only drawbacks are potential fungal acne triggers and it may not be hydrating enough for very dry skin types. At its price point, it offers impressive value compared to Western alternatives.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
A lightweight, fast-absorbing daily serum enriched with micro pantothenic acid (Vitamin B5) that delivers 7-second hydration while controlling excess oil and soothing irritated, acne-prone skin. Clinically proven to reduce breakouts by 62% in just 4 weeks.
โจ Texture & Feel
Micro Pantothenic Acid Technology
Ultra-fine vitamin B5 particles penetrate deeply to regulate sebum production and prevent clogged pores from the inside out.
7-Second Hydration System
Triple hyaluronic acid complex (sodium hyaluronate, hydrolyzed HA, and acetylated HA) delivers instant deep moisture without greasiness.
Soothing Booster 12 Complex
Patented blend featuring dipotassium glycyrrhizate, niacinamide, and sophora root extract for comprehensive anti-inflammatory care.
Barrier Strengthening Formula
Beta-glucan and centella asiatica work together to repair and reinforce the skin barrier while calming irritation and redness.
๐ก๏ธ Safety & Compatibility
No retinoids, salicylic acid, hydroquinone, or chemical sunscreens. All ingredients are considered safe for use during pregnancy and nursing.
Contains Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Jojoba Seed Oil which may feed malassezia yeast. Patch test recommended for FA-prone skin.
Clinically tested and confirmed non-comedogenic. Low comedogenic rating (1/5) means minimal risk of clogging pores.
Free from harsh alcohols, parabens, silicones, sulfates, and artificial fragrances. Enriched with soothing centella and allantoin.
Can be safely used with retinol, vitamin C, AHAs, and BHAs. Apply this serum first for hydration, then follow with actives.
Proven to reduce breakouts by 62.22% and excess oil by 37.41% in 4 weeks of clinical testing on acne-prone subjects.
๐ฌ Ingredient Breakdown
๐งฌ Pantothenic Acid (Vitamin B5) Micro-Particles Proven
The star ingredient that gives this serum its name. Pantothenic acid helps regulate sebum production and reduce inflammation associated with acne breakouts.
- Clinical Evidence: Studies show oral and topical B5 can significantly reduce acne lesions by controlling oil gland activity.
- Mechanism: Supports Coenzyme A synthesis, which is essential for metabolizing fatty acids and reducing sebum overproduction.
- Benefits: Oil control, anti-inflammatory, breakout prevention, skin healing support.
๐ Niacinamide (Vitamin B3) 4-5% Proven
A multi-tasking powerhouse that strengthens the skin barrier, regulates oil production, reduces pore appearance, and fades post-acne marks.
- Clinical Evidence: 4% niacinamide shown to significantly reduce sebum excretion and improve skin barrier function.
- Mechanism: Increases ceramide production, inhibits melanin transfer, and reduces inflammatory cytokines.
- Benefits: Oil control, brightening, pore minimizing, barrier repair, anti-aging.
๐ง Panthenol (Pro-Vitamin B5) 1.5-1.8% Proven
The precursor to pantothenic acid that provides deep hydration while soothing irritated and inflamed skin.
- Clinical Evidence: At 1-2% concentration, effectively improves skin hydration and reduces trans-epidermal water loss.
- Mechanism: Penetrates deep into skin layers, converts to pantothenic acid, and promotes lipid barrier synthesis.
- Benefits: Deep hydration, wound healing, anti-inflammatory, skin barrier support.
๐ Triple Hyaluronic Acid Complex Multi-Weight Proven
Three types of hyaluronic acid (Sodium Hyaluronate, Hydrolyzed HA, Sodium Acetylated Hyaluronate) provide multi-layer hydration.
- Sodium Hyaluronate: Mid-weight molecules for surface hydration and plumping.
- Hydrolyzed HA: Low molecular weight for deep penetration into skin layers.
- Sodium Acetylated HA: Enhanced adhesion for long-lasting moisture retention.
๐ Beta-Glucan Promising
A powerful soothing and hydrating ingredient derived from oats or yeast that calms inflammation and supports skin repair.
- Clinical Evidence: Studies show beta-glucan penetrates the epidermis and stimulates collagen synthesis.
- Benefits: Anti-inflammatory, wound healing, antioxidant, immune support for skin.
๐ฟ Centella Asiatica Extract Proven
The legendary "tiger grass" known for its powerful healing and soothing properties, containing asiaticoside and madecassic acid.
- Clinical Evidence: Extensively studied for wound healing, anti-inflammatory, and collagen synthesis properties.
- Benefits: Calms redness, promotes healing, strengthens skin barrier, antioxidant protection.
55 ingredients
Water, Butylene Glycol, Niacinamide, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Panthenol, Sophora Angustifolia Root Extract, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Propanediol, Diethoxyethyl Succinate, Tromethamine, Hydrogenated Lecithin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Betaine, Pantothenic Acid, Trehalose, Ethylhexylglycerin, Glyceryl Oleate, Sodium Phytate, Allantoin, Alpha-Arbutin, Houttuynia Cordata Extract, Lauryl Glucoside, Myristyl Glucoside, Polyglyceryl-6 Laurate, Zinc PCA, Melia Azadirachta Leaf Extract, Tocopherol, Glycyrrhiza Uralensis (Licorice) Root Extract, Melia Azadirachta Flower Extract, Coccinia Indica Fruit Extract, Centella Asiatica Extract, Sodium Hyaluronate, Citric Acid, Solanum Melongena (Eggplant) Fruit Extract, Beta-Glucan, Ocimum Sanctum Leaf Extract, Hyaluronic Acid, Decyl Glucoside, Curcuma Longa (Turmeric) Root Extract, Corallina Officinalis Extract, Dipotassium Glycyrrhizate, Hydrolyzed Hyaluronic Acid, Simmondsia Chinensis (Jojoba) Seed Oil, Camellia Sinensis Leaf Extract, Centella Asiatica Leaf Extract, Cladosiphon Okamuranus Extract, White Willow Bark Extract, Pinus Densiflora Leaf Extract, Coffea Arabica (Coffee) Seed Extract, Citrus Aurantium Bergamia Leaf Extract, Polyglyceryl-10 Stearate, Sodium Acetylated Hyaluronate, Beta-Sitosterol
๐ Where It Fits in Your Routine
Apply after toner on slightly damp skin. For best results, pair with numbuzin No.1 Pantothenic B5 Active Soothing Cream.
๐ How to Use
Cleanse & Prep
Start with a clean face. Apply your toner and let it partially absorb while skin is still slightly damp.
Dispense
Pump 2-3 drops of serum onto your fingertips. A little goes a long way with this concentrated formula.
Apply & Pat
Gently spread the serum across your face and neck, then pat gently to enhance absorption. Absorbs in 7 seconds.
Layer & Protect
Follow with moisturizer and sunscreen (AM). Can be used morning and night for optimal results.
๐ค Who Is It For?
โ Perfect for you if:
- You have oily or combination skin struggling with excess sebum
- You experience frequent breakouts and want to prevent new acne
- You need lightweight hydration that won't feel greasy
- You have sensitive, irritated, or redness-prone skin
- You want to balance oil production without over-drying
- You're looking for a gentle serum safe for daily use
- You want clinical-strength results in a K-beauty formula
โ Consider alternatives if:
- You have fungal acne (malassezia folliculitis) - contains potential triggers
- You have extremely dry skin needing heavy occlusive moisture
- You want a serum focused primarily on anti-aging or brightening
- You prefer products with a richer, cream-like texture
- You're looking for dramatic exfoliation effects
๐ฏ Skin Type Compatibility
Perfect match! Lightweight gel absorbs instantly without adding shine. Controls sebum production throughout the day.
Balances oily T-zone while providing adequate hydration to drier areas. Won't overwhelm either zone.
Clinically proven 62% reduction in breakouts. Non-comedogenic formula actively prevents new blemishes.
Fragrance-free with soothing centella and allantoin. Patch test recommended for very reactive skin.
Provides hydration but may feel lightweight for very dry skin. Layer with a richer moisturizer on top.
Niacinamide and hyaluronic acid provide anti-aging benefits. Best as part of a comprehensive routine.
๐ Results Timeline
Instant Hydration & Comfort
Skin feels immediately soothed and hydrated. The lightweight texture absorbs quickly without any sticky residue.
95% noticed immediate hydrationOil Control Begins
Noticeable reduction in midday shine and oiliness. Skin starts to feel more balanced throughout the day.
78% noticed less oilinessBreakout Reduction
Clinically proven 62.22% reduction in breakouts. Existing blemishes calm down and fewer new ones appear.
62% reduction in breakoutsClear, Balanced Skin
Significant improvement in overall skin clarity. Pores appear smaller, texture smooths out, and redness calms.
85% reported clearer skinโญ Ratings by Platform
โ๏ธ Pros & Cons
โ Praised
- Clinically proven to reduce breakouts by 62% in 4 weeks
- Ultra-lightweight texture absorbs in 7 seconds
- Effectively controls excess oil without over-drying
- Fragrance-free and gentle on sensitive skin
- Non-comedogenic and won't clog pores
- Works well under makeup without pilling
- Calms redness and inflammation quickly
- Pairs perfectly with the No.1 B5 Cream
โ Criticized
- May not be strong enough for extremely oily skin
- Contains potential fungal acne triggers
- 50ml bottle may run out quickly
- Some users found it slightly drying
- Results require consistent use for 4+ weeks
- Not ideal as a standalone moisturizer for dry skin
๐ฐ Budget-Friendly Alternatives (Dupes)
Similar centella-based soothing formula with panthenol. Slightly thicker texture and focuses more on barrier repair than oil control.
49% centella extract with niacinamide and peptides. More focused on soothing/anti-aging than sebum control. Fungal acne safe option.
French pharmacy option with vitamin B5 and hyaluronic acid. More focused on hydration/anti-aging than acne. Contains fragrance.
Propolis and centella formula for acne-prone skin. Moisturizer rather than serum format. Contains betaine salicylate for gentle exfoliation.
๐ Comparison with Competitors
Numbuzin No.1 B5 Serum (This Product)
$25.00COSRX Pure Fit Cica Serum
$18.00PURITO Centella Unscented Serum
$16.00La Roche-Posay Hyalu B5 Serum
$39.99๐ฆ Storage & Shelf Life
12 months after opening
Store in a cool, dry place away from direct sunlight. Keep out of reach of children.
Hygienic pump bottle with protective cap to prevent contamination and oxidation
Yes - 50ml is under the 100ml TSA liquid limit for carry-on luggage
โ Frequently Asked Questions
Yes, this serum is considered safe during pregnancy and breastfeeding. It does not contain any ingredients of concern such as retinoids, salicylic acid (in problematic concentrations), hydroquinone, or chemical sunscreen filters. The formula relies on gentle, pregnancy-safe ingredients like panthenol, niacinamide, and hyaluronic acid. However, as with any skincare product, it's always best to consult with your healthcare provider if you have specific concerns.
This serum contains some ingredients that may potentially trigger fungal acne, including Polyglyceryl-6 Laurate, Polyglyceryl-10 Stearate, and Simmondsia Chinensis (Jojoba) Seed Oil. If you have malassezia folliculitis, we recommend patch testing first or considering a fungal acne-safe alternative like PURITO Centella Unscented Serum. However, many users with acne-prone skin have reported excellent results, so individual responses may vary.
Yes! This serum is compatible with most active ingredients. Apply this serum first for hydration and soothing, then follow with your retinol, vitamin C, or chemical exfoliants. The panthenol and centella in this formula can actually help buffer potential irritation from stronger actives. For sensitive skin, consider alternating nights between this serum and stronger actives rather than layering them together.
This serum is best suited for oily, combination, and acne-prone skin types. It excels at oil control and breakout prevention while providing lightweight hydration. It also works well for sensitive skin due to its soothing ingredients. However, those with very dry skin may find it insufficient as a standalone hydrating product and should layer with a richer moisturizer. Mature skin can also benefit from the niacinamide and hyaluronic acid content.
You'll notice immediate hydration and comfort from the first use. Oil control benefits typically become apparent within 1-2 weeks of consistent use. For breakout reduction, clinical studies showed a 62.22% decrease in blemishes after 4 weeks of twice-daily application. Maximum benefits for skin clarity and texture are usually seen at 4-8 weeks of continuous use. Consistency is key for achieving the best results.
Apply this serum after cleansing and toning, while your skin is still slightly damp. It should go before thicker treatments, moisturizers, and sunscreen. The order is: Cleanser โ Toner โ This Serum โ Treatment serums (retinol, vitamin C) โ Moisturizer โ Sunscreen (AM). You can use it both morning and evening for best results.
No, this serum is clinically tested and confirmed to be non-comedogenic with a very low comedogenic rating of 1/5. The lightweight gel formula is specifically designed for acne-prone skin and absorbs quickly without leaving any residue that could clog pores. The pantothenic acid and niacinamide actually help regulate sebum production and keep pores clear.
The serum has a Period After Opening (PAO) of 12 months. The hygienic pump bottle helps protect the formula from contamination and oxidation. With twice-daily use (2-3 pumps per application), the 50ml bottle typically lasts 2-3 months. Store in a cool, dry place away from direct sunlight to maintain efficacy throughout the usage period.
Verdict: The Numbuzin No.1 Pantothenic B5 Active Soothing Serum is an excellent choice for oily and acne-prone skin seeking lightweight, effective sebum control. Backed by clinical testing showing 62% reduction in breakouts, it delivers on its promises while remaining gentle enough for sensitive skin. The 7-second absorption, fragrance-free formula, and multi-functional ingredients (pantothenic acid, niacinamide, hyaluronic acid) make it a standout in the K-beauty serum category. The only drawbacks are potential fungal acne triggers and it may not be hydrating enough for very dry skin types. At its price point, it offers impressive value compared to Western alternatives.
