
100% Squalane Oil
A weightless, multipurpose pure squalane oil derived from sustainable sugarcane that rapidly hydrates face, body, and hair. Bioidentical to skin's natural moisture, this single-ingredient powerhouse absorbs instantly while locking in essential hydration and helping other skincare actives work more effectively.
Instant Hydration
Absorbs rapidly without greasy residue
Bioidentical
Mimics skin's natural sebum
Multi-Purpose
Use on face, body, and hair
Barrier Support
Reinforces skin's protective layer
🔬 Ingredient Breakdown
🌿 Squalane (100%) Proven
A hydrogenated, stabilized form of squalene—a lipid naturally produced by human skin cells. Biossance's patented biotechnology creates pure squalane from renewable sugarcane, resulting in a highly stable, plant-derived emollient that's bioidentical to skin's own moisture.
- Clinical Study: 100% of participants showed increased cell renewal rate after 5 weeks of twice-daily use (35 subjects, ages 18-54)
- Hydration Study: 95% of users agreed skin felt instantly hydrated; 93% reported improved nourishment after 2 weeks (84 subjects)
- Research: Squalane reduces transepidermal water loss (TEWL) and supports skin barrier function (Archives of Dermatological Research)
- Safety: Non-irritating even at 100% concentration; safe for sensitive, acne-prone, and eczema-prone skin
📝 How to Use
For Face
Warm 2-3 drops between palms and gently pat onto cleansed face, neck, and décolleté. Apply as the last step in your skincare routine to lock in hydration. Can be mixed with moisturizer or serum for enhanced benefits.
For Body
Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas prone to dryness such as arms, legs, knees, and elbows. Great for post-sun exposure care.
For Hair
Rub a small amount between hands and smooth through dry or damp hair to add shine and tame flyaways, split ends, and frizz. Can also be applied to scalp for hydration.
👤 Who Is It For?
✅ Perfect for you if:
- You have dry, dehydrated, or tight-feeling skin
- You want a lightweight, non-greasy moisturizer
- You have sensitive or easily irritated skin
- You're looking for a multi-use product (face, body, hair)
- You have fungal acne or malassezia concerns
- You prefer clean, sustainable beauty products
- You want to boost effectiveness of other skincare products
- You have oily skin but need hydration without clogging pores
❌ Consider alternatives if:
- You need active anti-aging ingredients (retinol, vitamin C)
- You're on a strict budget (more affordable options exist)
- You prefer richer, heavier oils for very dry climates
- You want additional treatment benefits beyond hydration
- You prefer products with multiple active ingredients
📈 Results Timeline
Instant Hydration & Softness
Skin feels instantly moisturized, soft, and smooth. The lightweight formula absorbs within seconds without leaving greasy residue. Immediate reduction in tightness and discomfort from dryness.
95% noticed instant hydrationEnhanced Moisture Retention
Skin appears more nourished and hydrated throughout the day. Reduction in dry patches and flakiness. Improved overall skin texture and a healthy, natural glow.
93% reported improved nourishmentCellular Renewal & Barrier Support
Increased cell turnover rate leads to smoother, more radiant skin. Strengthened skin barrier function reduces sensitivity and moisture loss. Skin appears plumper and more resilient.
100% showed increased cell renewalLong-Term Skin Health
Maintained hydration levels and improved skin barrier integrity. Better tolerance of other active ingredients. Overall healthier, more balanced skin microbiome and reduced redness.
95% softer, smoother skin⭐ Ratings by Platform
| Platform | Rating | Reviews | 5★ | Main Complaint |
|---|---|---|---|---|
| Biossance.com | ★★★★★ 4.8 | 830+ | 85% | Premium price point |
| Sephora | ★★★★☆ 4.4 | 500+ | 72% | May feel too light for some |
| Influenster | ★★★★★ 4.8 | 1,600+ | 81% | Pump occasionally malfunctions |
| Amazon | ★★★★☆ 4.5 | 400+ | 75% | Cheaper alternatives available |
| MakeupAlley | ★★★★☆ 4.3 | 150+ | 70% | Single ingredient only |
⚖️ Pros & Cons
✅ Praised
- Ultra-lightweight, fast-absorbing formula
- No greasy or oily residue on skin
- Versatile use: face, body, and hair
- Completely fragrance-free
- Safe for all skin types including sensitive
- Fungal acne (malassezia) safe
- Sustainable sugarcane sourcing
- Convenient pump dispenser
- Excellent for boosting other products
- Vegan and cruelty-free certified
❌ Criticized
- Higher price than budget alternatives
- Single ingredient—no added actives
- May be too lightweight for very dry skin
- Pump mechanism can malfunction over time
- Some prefer thicker oil consistency
- Rare reports of breakouts (individual reaction)
- No anti-aging or treatment benefits
🔄 Comparison with Alternatives
| Feature | Biossance 100% Squalane | The Ordinary Squalane | Timeless Squalane |
|---|---|---|---|
| Price | $58 / 100ml | $9 / 30ml | $12 / 30ml |
| Source | Sugarcane | Plant-derived (unspecified) | Olive |
| Texture | Ultra-lightweight | Medium-weight | Medium-weight |
| Absorption | Very fast | Moderate | Moderate |
| Packaging | Pump bottle | Glass dropper | Glass dropper |
| Fungal Acne Safe | Yes | Yes | Possibly (olive source) |
| Clinical Studies | Yes (brand-sponsored) | No | No |
| Sustainability | Carbon-neutral, recyclable | Standard packaging | Standard packaging |
| Best For | Premium experience, multi-use | Budget-conscious users | Value seekers |
❓ Frequently Asked Questions
Squalene (with an "e") is naturally produced by your skin and is part of your skin's own moisture. However, it's unstable and oxidizes quickly. Squalane (with an "a") is the hydrogenated, stabilized version that has a longer shelf life and is more suitable for skincare formulations. Biossance's sugarcane-derived squalane offers the same moisturizing benefits without the stability issues.
Yes! Despite being an oil, squalane is non-comedogenic and won't clog pores. It's actually excellent for oily skin because it helps regulate sebum production and provides hydration without adding greasiness. The sugarcane source makes it particularly safe for those with fungal acne concerns.
Apply squalane as the last step in your skincare routine to lock in all previous products. After cleansing, toning, and applying serums and moisturizer, finish with 2-3 drops of squalane. You can also mix it directly into your moisturizer or apply it under makeup for added hydration.
Biossance's squalane is derived from sugarcane using patented biotechnology, ensuring consistent purity and quality. The brand conducts clinical studies, offers sustainable packaging, and maintains carbon-neutral practices. While budget alternatives work well for basic hydration, Biossance provides a premium experience with verified sourcing and environmental commitment.
Absolutely! Squalane is an excellent companion to active ingredients like retinol and vitamin C. It helps buffer potential irritation from these actives while enhancing their penetration into the skin. Apply your actives first, let them absorb, then seal with squalane.
Traditionally, squalene was harvested from shark livers, leading to the killing of millions of sharks annually. Biossance developed a plant-based alternative from renewable sugarcane that provides identical benefits without harming marine life. This innovation saves an estimated 2 million sharks per year.
Yes, 100% squalane is considered pregnancy-safe. It contains no active ingredients, retinoids, or potentially harmful chemicals. However, as with any skincare product, consult with your healthcare provider if you have specific concerns.
Verdict: Biossance 100% Squalane Oil is an exceptional single-ingredient moisturizer that delivers on its promise of lightweight, rapid hydration. Its sugarcane-derived formula is proven to be bioidentical to skin's natural oils, making it universally suitable for all skin types—including sensitive, oily, and acne-prone skin. Clinical studies back its effectiveness for improving hydration and cell renewal. While the premium price point may deter budget-conscious shoppers (The Ordinary offers a similar product at a fraction of the cost), Biossance justifies its positioning through superior sourcing, sustainability practices, and elegant packaging. Best suited for those who value clean beauty credentials and want a versatile, multi-use oil for face, body, and hair.
Original: $159,924.99
-70%$159,924.99
$47,977.50100% Squalane Oil
A weightless, multipurpose pure squalane oil derived from sustainable sugarcane that rapidly hydrates face, body, and hair. Bioidentical to skin's natural moisture, this single-ingredient powerhouse absorbs instantly while locking in essential hydration and helping other skincare actives work more effectively.
Instant Hydration
Absorbs rapidly without greasy residue
Bioidentical
Mimics skin's natural sebum
Multi-Purpose
Use on face, body, and hair
Barrier Support
Reinforces skin's protective layer
🔬 Ingredient Breakdown
🌿 Squalane (100%) Proven
A hydrogenated, stabilized form of squalene—a lipid naturally produced by human skin cells. Biossance's patented biotechnology creates pure squalane from renewable sugarcane, resulting in a highly stable, plant-derived emollient that's bioidentical to skin's own moisture.
- Clinical Study: 100% of participants showed increased cell renewal rate after 5 weeks of twice-daily use (35 subjects, ages 18-54)
- Hydration Study: 95% of users agreed skin felt instantly hydrated; 93% reported improved nourishment after 2 weeks (84 subjects)
- Research: Squalane reduces transepidermal water loss (TEWL) and supports skin barrier function (Archives of Dermatological Research)
- Safety: Non-irritating even at 100% concentration; safe for sensitive, acne-prone, and eczema-prone skin
📝 How to Use
For Face
Warm 2-3 drops between palms and gently pat onto cleansed face, neck, and décolleté. Apply as the last step in your skincare routine to lock in hydration. Can be mixed with moisturizer or serum for enhanced benefits.
For Body
Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas prone to dryness such as arms, legs, knees, and elbows. Great for post-sun exposure care.
For Hair
Rub a small amount between hands and smooth through dry or damp hair to add shine and tame flyaways, split ends, and frizz. Can also be applied to scalp for hydration.
👤 Who Is It For?
✅ Perfect for you if:
- You have dry, dehydrated, or tight-feeling skin
- You want a lightweight, non-greasy moisturizer
- You have sensitive or easily irritated skin
- You're looking for a multi-use product (face, body, hair)
- You have fungal acne or malassezia concerns
- You prefer clean, sustainable beauty products
- You want to boost effectiveness of other skincare products
- You have oily skin but need hydration without clogging pores
❌ Consider alternatives if:
- You need active anti-aging ingredients (retinol, vitamin C)
- You're on a strict budget (more affordable options exist)
- You prefer richer, heavier oils for very dry climates
- You want additional treatment benefits beyond hydration
- You prefer products with multiple active ingredients
📈 Results Timeline
Instant Hydration & Softness
Skin feels instantly moisturized, soft, and smooth. The lightweight formula absorbs within seconds without leaving greasy residue. Immediate reduction in tightness and discomfort from dryness.
95% noticed instant hydrationEnhanced Moisture Retention
Skin appears more nourished and hydrated throughout the day. Reduction in dry patches and flakiness. Improved overall skin texture and a healthy, natural glow.
93% reported improved nourishmentCellular Renewal & Barrier Support
Increased cell turnover rate leads to smoother, more radiant skin. Strengthened skin barrier function reduces sensitivity and moisture loss. Skin appears plumper and more resilient.
100% showed increased cell renewalLong-Term Skin Health
Maintained hydration levels and improved skin barrier integrity. Better tolerance of other active ingredients. Overall healthier, more balanced skin microbiome and reduced redness.
95% softer, smoother skin⭐ Ratings by Platform
| Platform | Rating | Reviews | 5★ | Main Complaint |
|---|---|---|---|---|
| Biossance.com | ★★★★★ 4.8 | 830+ | 85% | Premium price point |
| Sephora | ★★★★☆ 4.4 | 500+ | 72% | May feel too light for some |
| Influenster | ★★★★★ 4.8 | 1,600+ | 81% | Pump occasionally malfunctions |
| Amazon | ★★★★☆ 4.5 | 400+ | 75% | Cheaper alternatives available |
| MakeupAlley | ★★★★☆ 4.3 | 150+ | 70% | Single ingredient only |
⚖️ Pros & Cons
✅ Praised
- Ultra-lightweight, fast-absorbing formula
- No greasy or oily residue on skin
- Versatile use: face, body, and hair
- Completely fragrance-free
- Safe for all skin types including sensitive
- Fungal acne (malassezia) safe
- Sustainable sugarcane sourcing
- Convenient pump dispenser
- Excellent for boosting other products
- Vegan and cruelty-free certified
❌ Criticized
- Higher price than budget alternatives
- Single ingredient—no added actives
- May be too lightweight for very dry skin
- Pump mechanism can malfunction over time
- Some prefer thicker oil consistency
- Rare reports of breakouts (individual reaction)
- No anti-aging or treatment benefits
🔄 Comparison with Alternatives
| Feature | Biossance 100% Squalane | The Ordinary Squalane | Timeless Squalane |
|---|---|---|---|
| Price | $58 / 100ml | $9 / 30ml | $12 / 30ml |
| Source | Sugarcane | Plant-derived (unspecified) | Olive |
| Texture | Ultra-lightweight | Medium-weight | Medium-weight |
| Absorption | Very fast | Moderate | Moderate |
| Packaging | Pump bottle | Glass dropper | Glass dropper |
| Fungal Acne Safe | Yes | Yes | Possibly (olive source) |
| Clinical Studies | Yes (brand-sponsored) | No | No |
| Sustainability | Carbon-neutral, recyclable | Standard packaging | Standard packaging |
| Best For | Premium experience, multi-use | Budget-conscious users | Value seekers |
❓ Frequently Asked Questions
Squalene (with an "e") is naturally produced by your skin and is part of your skin's own moisture. However, it's unstable and oxidizes quickly. Squalane (with an "a") is the hydrogenated, stabilized version that has a longer shelf life and is more suitable for skincare formulations. Biossance's sugarcane-derived squalane offers the same moisturizing benefits without the stability issues.
Yes! Despite being an oil, squalane is non-comedogenic and won't clog pores. It's actually excellent for oily skin because it helps regulate sebum production and provides hydration without adding greasiness. The sugarcane source makes it particularly safe for those with fungal acne concerns.
Apply squalane as the last step in your skincare routine to lock in all previous products. After cleansing, toning, and applying serums and moisturizer, finish with 2-3 drops of squalane. You can also mix it directly into your moisturizer or apply it under makeup for added hydration.
Biossance's squalane is derived from sugarcane using patented biotechnology, ensuring consistent purity and quality. The brand conducts clinical studies, offers sustainable packaging, and maintains carbon-neutral practices. While budget alternatives work well for basic hydration, Biossance provides a premium experience with verified sourcing and environmental commitment.
Absolutely! Squalane is an excellent companion to active ingredients like retinol and vitamin C. It helps buffer potential irritation from these actives while enhancing their penetration into the skin. Apply your actives first, let them absorb, then seal with squalane.
Traditionally, squalene was harvested from shark livers, leading to the killing of millions of sharks annually. Biossance developed a plant-based alternative from renewable sugarcane that provides identical benefits without harming marine life. This innovation saves an estimated 2 million sharks per year.
Yes, 100% squalane is considered pregnancy-safe. It contains no active ingredients, retinoids, or potentially harmful chemicals. However, as with any skincare product, consult with your healthcare provider if you have specific concerns.
Verdict: Biossance 100% Squalane Oil is an exceptional single-ingredient moisturizer that delivers on its promise of lightweight, rapid hydration. Its sugarcane-derived formula is proven to be bioidentical to skin's natural oils, making it universally suitable for all skin types—including sensitive, oily, and acne-prone skin. Clinical studies back its effectiveness for improving hydration and cell renewal. While the premium price point may deter budget-conscious shoppers (The Ordinary offers a similar product at a fraction of the cost), Biossance justifies its positioning through superior sourcing, sustainability practices, and elegant packaging. Best suited for those who value clean beauty credentials and want a versatile, multi-use oil for face, body, and hair.
Product Information
Product Information
Shipping & Returns
Shipping & Returns
Description
A weightless, multipurpose pure squalane oil derived from sustainable sugarcane that rapidly hydrates face, body, and hair. Bioidentical to skin's natural moisture, this single-ingredient powerhouse absorbs instantly while locking in essential hydration and helping other skincare actives work more effectively.
Instant Hydration
Absorbs rapidly without greasy residue
Bioidentical
Mimics skin's natural sebum
Multi-Purpose
Use on face, body, and hair
Barrier Support
Reinforces skin's protective layer
🔬 Ingredient Breakdown
🌿 Squalane (100%) Proven
A hydrogenated, stabilized form of squalene—a lipid naturally produced by human skin cells. Biossance's patented biotechnology creates pure squalane from renewable sugarcane, resulting in a highly stable, plant-derived emollient that's bioidentical to skin's own moisture.
- Clinical Study: 100% of participants showed increased cell renewal rate after 5 weeks of twice-daily use (35 subjects, ages 18-54)
- Hydration Study: 95% of users agreed skin felt instantly hydrated; 93% reported improved nourishment after 2 weeks (84 subjects)
- Research: Squalane reduces transepidermal water loss (TEWL) and supports skin barrier function (Archives of Dermatological Research)
- Safety: Non-irritating even at 100% concentration; safe for sensitive, acne-prone, and eczema-prone skin
📝 How to Use
For Face
Warm 2-3 drops between palms and gently pat onto cleansed face, neck, and décolleté. Apply as the last step in your skincare routine to lock in hydration. Can be mixed with moisturizer or serum for enhanced benefits.
For Body
Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas prone to dryness such as arms, legs, knees, and elbows. Great for post-sun exposure care.
For Hair
Rub a small amount between hands and smooth through dry or damp hair to add shine and tame flyaways, split ends, and frizz. Can also be applied to scalp for hydration.
👤 Who Is It For?
✅ Perfect for you if:
- You have dry, dehydrated, or tight-feeling skin
- You want a lightweight, non-greasy moisturizer
- You have sensitive or easily irritated skin
- You're looking for a multi-use product (face, body, hair)
- You have fungal acne or malassezia concerns
- You prefer clean, sustainable beauty products
- You want to boost effectiveness of other skincare products
- You have oily skin but need hydration without clogging pores
❌ Consider alternatives if:
- You need active anti-aging ingredients (retinol, vitamin C)
- You're on a strict budget (more affordable options exist)
- You prefer richer, heavier oils for very dry climates
- You want additional treatment benefits beyond hydration
- You prefer products with multiple active ingredients
📈 Results Timeline
Instant Hydration & Softness
Skin feels instantly moisturized, soft, and smooth. The lightweight formula absorbs within seconds without leaving greasy residue. Immediate reduction in tightness and discomfort from dryness.
95% noticed instant hydrationEnhanced Moisture Retention
Skin appears more nourished and hydrated throughout the day. Reduction in dry patches and flakiness. Improved overall skin texture and a healthy, natural glow.
93% reported improved nourishmentCellular Renewal & Barrier Support
Increased cell turnover rate leads to smoother, more radiant skin. Strengthened skin barrier function reduces sensitivity and moisture loss. Skin appears plumper and more resilient.
100% showed increased cell renewalLong-Term Skin Health
Maintained hydration levels and improved skin barrier integrity. Better tolerance of other active ingredients. Overall healthier, more balanced skin microbiome and reduced redness.
95% softer, smoother skin⭐ Ratings by Platform
| Platform | Rating | Reviews | 5★ | Main Complaint |
|---|---|---|---|---|
| Biossance.com | ★★★★★ 4.8 | 830+ | 85% | Premium price point |
| Sephora | ★★★★☆ 4.4 | 500+ | 72% | May feel too light for some |
| Influenster | ★★★★★ 4.8 | 1,600+ | 81% | Pump occasionally malfunctions |
| Amazon | ★★★★☆ 4.5 | 400+ | 75% | Cheaper alternatives available |
| MakeupAlley | ★★★★☆ 4.3 | 150+ | 70% | Single ingredient only |
⚖️ Pros & Cons
✅ Praised
- Ultra-lightweight, fast-absorbing formula
- No greasy or oily residue on skin
- Versatile use: face, body, and hair
- Completely fragrance-free
- Safe for all skin types including sensitive
- Fungal acne (malassezia) safe
- Sustainable sugarcane sourcing
- Convenient pump dispenser
- Excellent for boosting other products
- Vegan and cruelty-free certified
❌ Criticized
- Higher price than budget alternatives
- Single ingredient—no added actives
- May be too lightweight for very dry skin
- Pump mechanism can malfunction over time
- Some prefer thicker oil consistency
- Rare reports of breakouts (individual reaction)
- No anti-aging or treatment benefits
🔄 Comparison with Alternatives
| Feature | Biossance 100% Squalane | The Ordinary Squalane | Timeless Squalane |
|---|---|---|---|
| Price | $58 / 100ml | $9 / 30ml | $12 / 30ml |
| Source | Sugarcane | Plant-derived (unspecified) | Olive |
| Texture | Ultra-lightweight | Medium-weight | Medium-weight |
| Absorption | Very fast | Moderate | Moderate |
| Packaging | Pump bottle | Glass dropper | Glass dropper |
| Fungal Acne Safe | Yes | Yes | Possibly (olive source) |
| Clinical Studies | Yes (brand-sponsored) | No | No |
| Sustainability | Carbon-neutral, recyclable | Standard packaging | Standard packaging |
| Best For | Premium experience, multi-use | Budget-conscious users | Value seekers |
❓ Frequently Asked Questions
Squalene (with an "e") is naturally produced by your skin and is part of your skin's own moisture. However, it's unstable and oxidizes quickly. Squalane (with an "a") is the hydrogenated, stabilized version that has a longer shelf life and is more suitable for skincare formulations. Biossance's sugarcane-derived squalane offers the same moisturizing benefits without the stability issues.
Yes! Despite being an oil, squalane is non-comedogenic and won't clog pores. It's actually excellent for oily skin because it helps regulate sebum production and provides hydration without adding greasiness. The sugarcane source makes it particularly safe for those with fungal acne concerns.
Apply squalane as the last step in your skincare routine to lock in all previous products. After cleansing, toning, and applying serums and moisturizer, finish with 2-3 drops of squalane. You can also mix it directly into your moisturizer or apply it under makeup for added hydration.
Biossance's squalane is derived from sugarcane using patented biotechnology, ensuring consistent purity and quality. The brand conducts clinical studies, offers sustainable packaging, and maintains carbon-neutral practices. While budget alternatives work well for basic hydration, Biossance provides a premium experience with verified sourcing and environmental commitment.
Absolutely! Squalane is an excellent companion to active ingredients like retinol and vitamin C. It helps buffer potential irritation from these actives while enhancing their penetration into the skin. Apply your actives first, let them absorb, then seal with squalane.
Traditionally, squalene was harvested from shark livers, leading to the killing of millions of sharks annually. Biossance developed a plant-based alternative from renewable sugarcane that provides identical benefits without harming marine life. This innovation saves an estimated 2 million sharks per year.
Yes, 100% squalane is considered pregnancy-safe. It contains no active ingredients, retinoids, or potentially harmful chemicals. However, as with any skincare product, consult with your healthcare provider if you have specific concerns.
Verdict: Biossance 100% Squalane Oil is an exceptional single-ingredient moisturizer that delivers on its promise of lightweight, rapid hydration. Its sugarcane-derived formula is proven to be bioidentical to skin's natural oils, making it universally suitable for all skin types—including sensitive, oily, and acne-prone skin. Clinical studies back its effectiveness for improving hydration and cell renewal. While the premium price point may deter budget-conscious shoppers (The Ordinary offers a similar product at a fraction of the cost), Biossance justifies its positioning through superior sourcing, sustainability practices, and elegant packaging. Best suited for those who value clean beauty credentials and want a versatile, multi-use oil for face, body, and hair.




