100% Sugarcane Squalane Oil
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100% Sugarcane Squalane Oil

100% Sugarcane Squalane Oil

A weightless, multi-tasking pure squalane oil harvested from renewable sugarcane that rapidly hydrates from head to toe. This bioidentical moisture locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

πŸ‡ΊπŸ‡Έ Clean Beauty Β· Made in USA
βœ” 100% Squalane βœ” Vegan βœ” Cruelty-Free βœ” EWG Verified βœ” Fragrance-Free βœ” Non-Comedogenic βœ” Dermatologist Tested βœ” Saves 2M Sharks/Year
Pregnancy Safe
Yes βœ”
Fungal Acne Safe
Yes βœ”
Comedogenic Rating
1/5
πŸ“¦
Size
100ml / 3.3 oz
🎯
Concerns
Dryness, Redness
πŸ’§
Formula
Lightweight Oil
🌱
Source
Sugarcane
βš—οΈ
Active
Squalane 100%

✨ Texture & Feel

πŸ’§
Consistency
Lightweight Oil
πŸ‘ƒ
Scent
Fragrance-Free
⏱️
Absorption
Instant
🎯
Finish
Dewy, Non-Greasy
πŸ’§

Bioidentical Moisture

Mimics your skin's natural moisture, making it weightless and instantly absorbed without leaving a greasy residue.

πŸ”¬

Boosts Absorption

Helps other active ingredients penetrate more deeply and work more effectively when layered underneath.

🌿

Sustainable Sugarcane

Derived from renewable sugarcane using patented biotechnology, saving 2 million sharks per year from harvesting.

✨

Multi-Purpose Use

Perfect for face, body, and hair. Tames flyaways, soothes dry patches, and adds healthy-looking shine everywhere.

πŸ›‘οΈ Safety & Compatibility

βœ…
Pregnancy & Breastfeeding Safe

Squalane is considered safe during pregnancy and nursing. Contains no retinoids, salicylic acid, or harmful ingredients. Named best pregnancy-safe skincare brand by The Bump 2024.

βœ…
Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a saturated hydrocarbon that does not feed Malassezia yeast. The purest form for fungal acne-prone skin.

βœ…
Non-Comedogenic

Rating 1/5. Will not clog pores. Suitable for acne-prone skin and helps balance natural oil production.

βœ…
Sensitive Skin Friendly

Hypoallergenic and dermatologist tested. Non-irritating even at 100% concentration according to CIR safety data.

ℹ️
Clean Formula

Biossance bans over 2,000 potentially toxic ingredients. EWG-verified and free from parabens, sulfates, and phthalates.

ℹ️
Compatible With All Actives

Safe to use with retinol, vitamin C, AHAs, BHAs, and niacinamide. Actually enhances penetration of other products.

πŸ”¬ Ingredient Breakdown

🌿 Squalane (Sugarcane-Derived) 100% Proven

A saturated hydrocarbon that mimics the squalene naturally found in human sebum. This bioidentical moisturizer instantly hydrates while locking in essential moisture. Your body produces its own squalene, but production decreases with age.

  • Molecular Structure: Saturated C30 hydrocarbon with excellent oxidative stability
  • Source: Patented bio-fermentation from Brazilian sugarcane (farnesene precursor)
  • CIR Assessment: Safe as cosmetic ingredient at up to 100% concentration
  • Clinical Benefit: Prevents transepidermal water loss (TEWL) while remaining lightweight
  • Skin Benefit: Promotes microbiome diversity for healthier-looking skin
✨
Sugarcane-derived squalane is purer and more stable than olive-derived versions, making it the preferred choice for sensitive and fungal acne-prone skin.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrance, Essential Oils, Silicones, Mineral Oil, PEGs, Formaldehyde, Hydroquinone, Triclosan, Triclocarban, Coal Tar, Oxybenzone, BHA, BHT, Ethanolamines, Retinoids, Animal-Derived Ingredients

πŸ”„ Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Serum
4
Moisturizer
5
Squalane Oil
6
Sunscreen (AM)

Apply as the final step to lock in hydration. Can also be mixed with moisturizer or applied directly on damp skin for enhanced absorption.

πŸ“ How to Use

1

For Face

Rub a small amount (2-3 drops) between hands to warm. Pat gently onto face, neck, and dΓ©colletΓ© as your final skincare step.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas needing extra hydration like arms, legs, and knees.

3

For Hair

Rub a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz.

4

Pro Tip

Apply on damp skin for optimal absorption. Mix with your favorite moisturizer for a hydration boost, or add a drop to foundation for a dewy finish.

πŸ‘€ Who Is It For?

βœ… Perfect for you if:

  • You have dry, dehydrated, or dull skin
  • You want a simple, one-ingredient moisturizer
  • You need a pregnancy or breastfeeding safe option
  • You have fungal acne or Malassezia concerns
  • You want a multi-purpose product for face, body, and hair
  • You prefer clean, sustainable beauty products
  • You have sensitive or reactive skin
  • You want to boost other product absorption

❌ Consider alternatives if:

  • You prefer heavier, richer moisturizers
  • You want additional active ingredients like vitamin C
  • You're on a very tight budget (more affordable dupes exist)
  • You dislike oil textures entirely

🎯 Skin Type Compatibility

Oily Skin β˜…β˜…β˜…β˜…β˜… Excellent

Lightweight formula absorbs instantly without adding shine. Helps balance natural oil production rather than exacerbating it.

Dry Skin β˜…β˜…β˜…β˜…β˜… Excellent

Locks in moisture and prevents water loss. Use generously on extra-dry areas. Layer with a heavier cream in winter if needed.

Combination Skin β˜…β˜…β˜…β˜…β˜… Excellent

Adapts to different zones perfectly. Hydrates dry areas without making oily zones greasy.

Sensitive Skin β˜…β˜…β˜…β˜…β˜… Excellent

Single ingredient formula minimizes irritation risk. Hypoallergenic and dermatologist tested. Helps calm redness.

Acne-Prone Skin β˜…β˜…β˜…β˜…β˜… Excellent

Non-comedogenic and fungal acne safe. Many users report it helps clear clogged pores rather than causing breakouts.

πŸ“ˆ Results Timeline

Immediately

Instant Hydration

Skin feels instantly moisturized and soft. Absorbs within seconds without greasy residue.

95% noticed
1 Week

Softer, Smoother Texture

Skin appears softer and smoother. Rough patches begin to diminish. Makeup applies more evenly.

95% noticed
2 Weeks

Improved Nourishment

Skin feels deeply nourished and hydrated throughout the day. Visible reduction in dry flakes and tightness.

93% noticed
5 Weeks

Enhanced Cell Renewal

Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

100% clinically proven

⭐ Ratings by Platform

πŸ’„ Sephora
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
831+
Reviews
⚠️ Main complaint: Higher price point compared to competitors offering similar single-ingredient formulas
πŸ›’ Amazon
β˜…β˜…β˜…β˜…β˜… 4.6
Rating
5,000+
Reviews
⚠️ Main complaint: Pump dispenses more product than needed for face-only use
🏠 Biossance Website
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
900+
Reviews
⚠️ Main complaint: Wish there was an even larger size for full-body application
✨ Influenster
β˜…β˜…β˜…β˜…β˜… 4.7
Rating
2,500+
Reviews
⚠️ Main complaint: Works so well users feel compelled to try other Biossance products (expensive habit!)

βš–οΈ Pros & Cons

βœ… Praised

  • Ultra-lightweight and fast-absorbing
  • Single pure ingredient - minimal reaction risk
  • Multi-purpose for face, body, and hair
  • Pregnancy and breastfeeding safe
  • Fungal acne safe (sugarcane source)
  • Non-comedogenic and non-greasy
  • Sustainable and cruelty-free
  • Large 100ml bottle with convenient pump
  • Works under makeup without pilling
  • Visibly calms redness and irritation

❌ Criticized

  • Higher price than The Ordinary alternative
  • Pump may dispense too much product
  • Very dry skin may need additional moisturizer
  • Minimal active benefits beyond hydration
  • No dropper option for precise application

πŸ’° Budget-Friendly Alternatives (Dupes)

95% Match
The Ordinary 100% Plant-Derived Squalane
$7.90 Budget Pick

Nearly identical single-ingredient formula. Plant-derived but source unspecified (may be olive). Dropper bottle instead of pump. Slightly thicker texture that takes a bit longer to absorb.

90% Match
Timeless Squalane Oil 100% Pure
$12.00 Budget Pick

Olive-derived squalane with excellent reviews. Medium-weight texture, great as makeup primer. Glass dropper bottle. May not be ideal for severe fungal acne concerns due to olive source.

88% Match
Good Molecules Squalane Oil
$8.00 Budget Pick

Olive-derived 100% squalane. Thicker consistency that still absorbs well. Smaller bottle size but excellent value. Fun, colorful packaging.

75% Match
Indeed Labs Squalane Facial Oil
$14.99 Similar Price

Sugarcane-derived like Biossance with ultra-light "dry oil" texture. Excellent for oily skin. Smaller bottle but clinical-grade quality with anti-aging claims.

πŸ”„ Comparison with Competitors

The Ordinary 100% Squalane

$7.90
Key Ingredient Squalane 100%
Source Plant (unspecified)
Size 30ml
Cost per oz $7.90/oz
Fungal Acne Safe Likely βœ”
Packaging Glass dropper

Timeless Squalane Oil

$12.00
Key Ingredient Squalane 100%
Source Olive
Size 60ml
Cost per oz $6.00/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

Good Molecules Squalane

$8.00
Key Ingredient Squalane 100%
Source Olive
Size 13ml
Cost per oz $18.46/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

πŸ“¦ Storage & Shelf Life

πŸ“…
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration needed. Squalane is highly stable.

πŸ“¦
Packaging

Recyclable plastic pump bottle. Outer carton made from FSC-certified sugarcane paper.

✈️
Travel Friendly

Yes, the 100ml size meets TSA carry-on liquid requirements

❓ Frequently Asked Questions

Yes, absolutely. Biossance 100% Squalane Oil is pregnancy and breastfeeding safe. Squalane contains no retinoids, salicylic acid, hydroquinone, or any ingredients that are contraindicated during pregnancy. In fact, Biossance was named the best pregnancy-safe skincare brand by The Bump in 2024, and dermatologist Dr. Alexis Stephens specifically recommends this product for preventing stretch marks during pregnancy.

Yes. Sugarcane-derived squalane like Biossance's is considered safe for fungal acne-prone skin. Unlike olive-derived squalane which may contain trace impurities, sugarcane squalane is synthesized via bio-fermentation resulting in approximately 99% pure hydrocarbons with no fatty acids that Malassezia can metabolize. It's a saturated hydrocarbon that does not feed the yeast that causes fungal acne.

Yes! Squalane is compatible with all skincare actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. In fact, squalane helps boost the absorption of other active ingredients and enables them to work more effectively. Apply your active treatments first, then seal everything in with squalane as your final step.

Biossance 100% Squalane Oil works excellently for all skin types: normal, dry, combination, oily, sensitive, and acne-prone. The lightweight, fast-absorbing formula adapts to different skin needs - it hydrates dry areas without making oily zones greasy. It's particularly loved by those with sensitive skin due to its single-ingredient formula and hypoallergenic properties.

Results are immediate and progressive. You'll notice instant hydration and softness right away. After 1 week, skin appears softer and smoother. By 2 weeks, 93% of users reported more nourished, hydrated skin. Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

Apply squalane oil as your final step after cleansing, toning, serums, and moisturizer. It acts as a "seal" to lock in all your previous products. For daytime, apply before sunscreen. You can also mix a drop into your moisturizer or foundation, or apply directly to damp skin after cleansing for enhanced absorption.

No, Biossance 100% Squalane Oil is non-comedogenic with a rating of 1/5. Despite being an oil, squalane actually helps balance natural oil production rather than clog pores. Many users with acne-prone skin report that it helps clear clogged pores and reduces breakouts. The product is dermatologist tested and suitable for acne-prone skin.

The product has a 12-month (12M) Period After Opening (PAO). Squalane is highly stable and resistant to oxidation, unlike many other oils. Store in a cool, dry place away from direct sunlight. The pump bottle design also helps protect the product from air exposure and contamination.

β˜…β˜…β˜…β˜…β˜…
4.8 out of 5

Verdict: Biossance 100% Sugarcane Squalane Oil is the gold standard for pure squalane face oils. While budget alternatives like The Ordinary exist, Biossance justifies its premium with certified sugarcane sourcing (ideal for fungal acne), convenient pump packaging, and the ethical peace of mind knowing you're saving sharks. The single-ingredient formula makes it universally safe for pregnancy, sensitive skin, and virtually every skin type. If you want the purest, most sustainable squalane with clinical backing, this is the one to choose. For budget-conscious shoppers, The Ordinary offers 95% of the benefits at a fraction of the cost.

$4.84

Original: $16.15

-70%
100% Sugarcane Squalane Oilβ€”

$16.15

$4.84

100% Sugarcane Squalane Oil

A weightless, multi-tasking pure squalane oil harvested from renewable sugarcane that rapidly hydrates from head to toe. This bioidentical moisture locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

πŸ‡ΊπŸ‡Έ Clean Beauty Β· Made in USA
βœ” 100% Squalane βœ” Vegan βœ” Cruelty-Free βœ” EWG Verified βœ” Fragrance-Free βœ” Non-Comedogenic βœ” Dermatologist Tested βœ” Saves 2M Sharks/Year
Pregnancy Safe
Yes βœ”
Fungal Acne Safe
Yes βœ”
Comedogenic Rating
1/5
πŸ“¦
Size
100ml / 3.3 oz
🎯
Concerns
Dryness, Redness
πŸ’§
Formula
Lightweight Oil
🌱
Source
Sugarcane
βš—οΈ
Active
Squalane 100%

✨ Texture & Feel

πŸ’§
Consistency
Lightweight Oil
πŸ‘ƒ
Scent
Fragrance-Free
⏱️
Absorption
Instant
🎯
Finish
Dewy, Non-Greasy
πŸ’§

Bioidentical Moisture

Mimics your skin's natural moisture, making it weightless and instantly absorbed without leaving a greasy residue.

πŸ”¬

Boosts Absorption

Helps other active ingredients penetrate more deeply and work more effectively when layered underneath.

🌿

Sustainable Sugarcane

Derived from renewable sugarcane using patented biotechnology, saving 2 million sharks per year from harvesting.

✨

Multi-Purpose Use

Perfect for face, body, and hair. Tames flyaways, soothes dry patches, and adds healthy-looking shine everywhere.

πŸ›‘οΈ Safety & Compatibility

βœ…
Pregnancy & Breastfeeding Safe

Squalane is considered safe during pregnancy and nursing. Contains no retinoids, salicylic acid, or harmful ingredients. Named best pregnancy-safe skincare brand by The Bump 2024.

βœ…
Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a saturated hydrocarbon that does not feed Malassezia yeast. The purest form for fungal acne-prone skin.

βœ…
Non-Comedogenic

Rating 1/5. Will not clog pores. Suitable for acne-prone skin and helps balance natural oil production.

βœ…
Sensitive Skin Friendly

Hypoallergenic and dermatologist tested. Non-irritating even at 100% concentration according to CIR safety data.

ℹ️
Clean Formula

Biossance bans over 2,000 potentially toxic ingredients. EWG-verified and free from parabens, sulfates, and phthalates.

ℹ️
Compatible With All Actives

Safe to use with retinol, vitamin C, AHAs, BHAs, and niacinamide. Actually enhances penetration of other products.

πŸ”¬ Ingredient Breakdown

🌿 Squalane (Sugarcane-Derived) 100% Proven

A saturated hydrocarbon that mimics the squalene naturally found in human sebum. This bioidentical moisturizer instantly hydrates while locking in essential moisture. Your body produces its own squalene, but production decreases with age.

  • Molecular Structure: Saturated C30 hydrocarbon with excellent oxidative stability
  • Source: Patented bio-fermentation from Brazilian sugarcane (farnesene precursor)
  • CIR Assessment: Safe as cosmetic ingredient at up to 100% concentration
  • Clinical Benefit: Prevents transepidermal water loss (TEWL) while remaining lightweight
  • Skin Benefit: Promotes microbiome diversity for healthier-looking skin
✨
Sugarcane-derived squalane is purer and more stable than olive-derived versions, making it the preferred choice for sensitive and fungal acne-prone skin.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrance, Essential Oils, Silicones, Mineral Oil, PEGs, Formaldehyde, Hydroquinone, Triclosan, Triclocarban, Coal Tar, Oxybenzone, BHA, BHT, Ethanolamines, Retinoids, Animal-Derived Ingredients

πŸ”„ Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Serum
4
Moisturizer
5
Squalane Oil
6
Sunscreen (AM)

Apply as the final step to lock in hydration. Can also be mixed with moisturizer or applied directly on damp skin for enhanced absorption.

πŸ“ How to Use

1

For Face

Rub a small amount (2-3 drops) between hands to warm. Pat gently onto face, neck, and dΓ©colletΓ© as your final skincare step.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas needing extra hydration like arms, legs, and knees.

3

For Hair

Rub a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz.

4

Pro Tip

Apply on damp skin for optimal absorption. Mix with your favorite moisturizer for a hydration boost, or add a drop to foundation for a dewy finish.

πŸ‘€ Who Is It For?

βœ… Perfect for you if:

  • You have dry, dehydrated, or dull skin
  • You want a simple, one-ingredient moisturizer
  • You need a pregnancy or breastfeeding safe option
  • You have fungal acne or Malassezia concerns
  • You want a multi-purpose product for face, body, and hair
  • You prefer clean, sustainable beauty products
  • You have sensitive or reactive skin
  • You want to boost other product absorption

❌ Consider alternatives if:

  • You prefer heavier, richer moisturizers
  • You want additional active ingredients like vitamin C
  • You're on a very tight budget (more affordable dupes exist)
  • You dislike oil textures entirely

🎯 Skin Type Compatibility

Oily Skin β˜…β˜…β˜…β˜…β˜… Excellent

Lightweight formula absorbs instantly without adding shine. Helps balance natural oil production rather than exacerbating it.

Dry Skin β˜…β˜…β˜…β˜…β˜… Excellent

Locks in moisture and prevents water loss. Use generously on extra-dry areas. Layer with a heavier cream in winter if needed.

Combination Skin β˜…β˜…β˜…β˜…β˜… Excellent

Adapts to different zones perfectly. Hydrates dry areas without making oily zones greasy.

Sensitive Skin β˜…β˜…β˜…β˜…β˜… Excellent

Single ingredient formula minimizes irritation risk. Hypoallergenic and dermatologist tested. Helps calm redness.

Acne-Prone Skin β˜…β˜…β˜…β˜…β˜… Excellent

Non-comedogenic and fungal acne safe. Many users report it helps clear clogged pores rather than causing breakouts.

πŸ“ˆ Results Timeline

Immediately

Instant Hydration

Skin feels instantly moisturized and soft. Absorbs within seconds without greasy residue.

95% noticed
1 Week

Softer, Smoother Texture

Skin appears softer and smoother. Rough patches begin to diminish. Makeup applies more evenly.

95% noticed
2 Weeks

Improved Nourishment

Skin feels deeply nourished and hydrated throughout the day. Visible reduction in dry flakes and tightness.

93% noticed
5 Weeks

Enhanced Cell Renewal

Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

100% clinically proven

⭐ Ratings by Platform

πŸ’„ Sephora
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
831+
Reviews
⚠️ Main complaint: Higher price point compared to competitors offering similar single-ingredient formulas
πŸ›’ Amazon
β˜…β˜…β˜…β˜…β˜… 4.6
Rating
5,000+
Reviews
⚠️ Main complaint: Pump dispenses more product than needed for face-only use
🏠 Biossance Website
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
900+
Reviews
⚠️ Main complaint: Wish there was an even larger size for full-body application
✨ Influenster
β˜…β˜…β˜…β˜…β˜… 4.7
Rating
2,500+
Reviews
⚠️ Main complaint: Works so well users feel compelled to try other Biossance products (expensive habit!)

βš–οΈ Pros & Cons

βœ… Praised

  • Ultra-lightweight and fast-absorbing
  • Single pure ingredient - minimal reaction risk
  • Multi-purpose for face, body, and hair
  • Pregnancy and breastfeeding safe
  • Fungal acne safe (sugarcane source)
  • Non-comedogenic and non-greasy
  • Sustainable and cruelty-free
  • Large 100ml bottle with convenient pump
  • Works under makeup without pilling
  • Visibly calms redness and irritation

❌ Criticized

  • Higher price than The Ordinary alternative
  • Pump may dispense too much product
  • Very dry skin may need additional moisturizer
  • Minimal active benefits beyond hydration
  • No dropper option for precise application

πŸ’° Budget-Friendly Alternatives (Dupes)

95% Match
The Ordinary 100% Plant-Derived Squalane
$7.90 Budget Pick

Nearly identical single-ingredient formula. Plant-derived but source unspecified (may be olive). Dropper bottle instead of pump. Slightly thicker texture that takes a bit longer to absorb.

90% Match
Timeless Squalane Oil 100% Pure
$12.00 Budget Pick

Olive-derived squalane with excellent reviews. Medium-weight texture, great as makeup primer. Glass dropper bottle. May not be ideal for severe fungal acne concerns due to olive source.

88% Match
Good Molecules Squalane Oil
$8.00 Budget Pick

Olive-derived 100% squalane. Thicker consistency that still absorbs well. Smaller bottle size but excellent value. Fun, colorful packaging.

75% Match
Indeed Labs Squalane Facial Oil
$14.99 Similar Price

Sugarcane-derived like Biossance with ultra-light "dry oil" texture. Excellent for oily skin. Smaller bottle but clinical-grade quality with anti-aging claims.

πŸ”„ Comparison with Competitors

The Ordinary 100% Squalane

$7.90
Key Ingredient Squalane 100%
Source Plant (unspecified)
Size 30ml
Cost per oz $7.90/oz
Fungal Acne Safe Likely βœ”
Packaging Glass dropper

Timeless Squalane Oil

$12.00
Key Ingredient Squalane 100%
Source Olive
Size 60ml
Cost per oz $6.00/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

Good Molecules Squalane

$8.00
Key Ingredient Squalane 100%
Source Olive
Size 13ml
Cost per oz $18.46/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

πŸ“¦ Storage & Shelf Life

πŸ“…
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration needed. Squalane is highly stable.

πŸ“¦
Packaging

Recyclable plastic pump bottle. Outer carton made from FSC-certified sugarcane paper.

✈️
Travel Friendly

Yes, the 100ml size meets TSA carry-on liquid requirements

❓ Frequently Asked Questions

Yes, absolutely. Biossance 100% Squalane Oil is pregnancy and breastfeeding safe. Squalane contains no retinoids, salicylic acid, hydroquinone, or any ingredients that are contraindicated during pregnancy. In fact, Biossance was named the best pregnancy-safe skincare brand by The Bump in 2024, and dermatologist Dr. Alexis Stephens specifically recommends this product for preventing stretch marks during pregnancy.

Yes. Sugarcane-derived squalane like Biossance's is considered safe for fungal acne-prone skin. Unlike olive-derived squalane which may contain trace impurities, sugarcane squalane is synthesized via bio-fermentation resulting in approximately 99% pure hydrocarbons with no fatty acids that Malassezia can metabolize. It's a saturated hydrocarbon that does not feed the yeast that causes fungal acne.

Yes! Squalane is compatible with all skincare actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. In fact, squalane helps boost the absorption of other active ingredients and enables them to work more effectively. Apply your active treatments first, then seal everything in with squalane as your final step.

Biossance 100% Squalane Oil works excellently for all skin types: normal, dry, combination, oily, sensitive, and acne-prone. The lightweight, fast-absorbing formula adapts to different skin needs - it hydrates dry areas without making oily zones greasy. It's particularly loved by those with sensitive skin due to its single-ingredient formula and hypoallergenic properties.

Results are immediate and progressive. You'll notice instant hydration and softness right away. After 1 week, skin appears softer and smoother. By 2 weeks, 93% of users reported more nourished, hydrated skin. Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

Apply squalane oil as your final step after cleansing, toning, serums, and moisturizer. It acts as a "seal" to lock in all your previous products. For daytime, apply before sunscreen. You can also mix a drop into your moisturizer or foundation, or apply directly to damp skin after cleansing for enhanced absorption.

No, Biossance 100% Squalane Oil is non-comedogenic with a rating of 1/5. Despite being an oil, squalane actually helps balance natural oil production rather than clog pores. Many users with acne-prone skin report that it helps clear clogged pores and reduces breakouts. The product is dermatologist tested and suitable for acne-prone skin.

The product has a 12-month (12M) Period After Opening (PAO). Squalane is highly stable and resistant to oxidation, unlike many other oils. Store in a cool, dry place away from direct sunlight. The pump bottle design also helps protect the product from air exposure and contamination.

β˜…β˜…β˜…β˜…β˜…
4.8 out of 5

Verdict: Biossance 100% Sugarcane Squalane Oil is the gold standard for pure squalane face oils. While budget alternatives like The Ordinary exist, Biossance justifies its premium with certified sugarcane sourcing (ideal for fungal acne), convenient pump packaging, and the ethical peace of mind knowing you're saving sharks. The single-ingredient formula makes it universally safe for pregnancy, sensitive skin, and virtually every skin type. If you want the purest, most sustainable squalane with clinical backing, this is the one to choose. For budget-conscious shoppers, The Ordinary offers 95% of the benefits at a fraction of the cost.

Product Information

Shipping & Returns

Description

A weightless, multi-tasking pure squalane oil harvested from renewable sugarcane that rapidly hydrates from head to toe. This bioidentical moisture locks in hydration, boosts absorption of other actives, and promotes microbiome diversity for healthier-looking skin.

πŸ‡ΊπŸ‡Έ Clean Beauty Β· Made in USA
βœ” 100% Squalane βœ” Vegan βœ” Cruelty-Free βœ” EWG Verified βœ” Fragrance-Free βœ” Non-Comedogenic βœ” Dermatologist Tested βœ” Saves 2M Sharks/Year
Pregnancy Safe
Yes βœ”
Fungal Acne Safe
Yes βœ”
Comedogenic Rating
1/5
πŸ“¦
Size
100ml / 3.3 oz
🎯
Concerns
Dryness, Redness
πŸ’§
Formula
Lightweight Oil
🌱
Source
Sugarcane
βš—οΈ
Active
Squalane 100%

✨ Texture & Feel

πŸ’§
Consistency
Lightweight Oil
πŸ‘ƒ
Scent
Fragrance-Free
⏱️
Absorption
Instant
🎯
Finish
Dewy, Non-Greasy
πŸ’§

Bioidentical Moisture

Mimics your skin's natural moisture, making it weightless and instantly absorbed without leaving a greasy residue.

πŸ”¬

Boosts Absorption

Helps other active ingredients penetrate more deeply and work more effectively when layered underneath.

🌿

Sustainable Sugarcane

Derived from renewable sugarcane using patented biotechnology, saving 2 million sharks per year from harvesting.

✨

Multi-Purpose Use

Perfect for face, body, and hair. Tames flyaways, soothes dry patches, and adds healthy-looking shine everywhere.

πŸ›‘οΈ Safety & Compatibility

βœ…
Pregnancy & Breastfeeding Safe

Squalane is considered safe during pregnancy and nursing. Contains no retinoids, salicylic acid, or harmful ingredients. Named best pregnancy-safe skincare brand by The Bump 2024.

βœ…
Fungal Acne (Malassezia) Safe

Sugarcane-derived squalane is a saturated hydrocarbon that does not feed Malassezia yeast. The purest form for fungal acne-prone skin.

βœ…
Non-Comedogenic

Rating 1/5. Will not clog pores. Suitable for acne-prone skin and helps balance natural oil production.

βœ…
Sensitive Skin Friendly

Hypoallergenic and dermatologist tested. Non-irritating even at 100% concentration according to CIR safety data.

ℹ️
Clean Formula

Biossance bans over 2,000 potentially toxic ingredients. EWG-verified and free from parabens, sulfates, and phthalates.

ℹ️
Compatible With All Actives

Safe to use with retinol, vitamin C, AHAs, BHAs, and niacinamide. Actually enhances penetration of other products.

πŸ”¬ Ingredient Breakdown

🌿 Squalane (Sugarcane-Derived) 100% Proven

A saturated hydrocarbon that mimics the squalene naturally found in human sebum. This bioidentical moisturizer instantly hydrates while locking in essential moisture. Your body produces its own squalene, but production decreases with age.

  • Molecular Structure: Saturated C30 hydrocarbon with excellent oxidative stability
  • Source: Patented bio-fermentation from Brazilian sugarcane (farnesene precursor)
  • CIR Assessment: Safe as cosmetic ingredient at up to 100% concentration
  • Clinical Benefit: Prevents transepidermal water loss (TEWL) while remaining lightweight
  • Skin Benefit: Promotes microbiome diversity for healthier-looking skin
✨
Sugarcane-derived squalane is purer and more stable than olive-derived versions, making it the preferred choice for sensitive and fungal acne-prone skin.

1 ingredient

Squalane

FREE FROM: Parabens, Sulfates, Phthalates, Fragrance, Essential Oils, Silicones, Mineral Oil, PEGs, Formaldehyde, Hydroquinone, Triclosan, Triclocarban, Coal Tar, Oxybenzone, BHA, BHT, Ethanolamines, Retinoids, Animal-Derived Ingredients

πŸ”„ Where It Fits in Your Routine

1
Cleanser
2
Toner
3
Serum
4
Moisturizer
5
Squalane Oil
6
Sunscreen (AM)

Apply as the final step to lock in hydration. Can also be mixed with moisturizer or applied directly on damp skin for enhanced absorption.

πŸ“ How to Use

1

For Face

Rub a small amount (2-3 drops) between hands to warm. Pat gently onto face, neck, and dΓ©colletΓ© as your final skincare step.

2

For Body

Massage a few pumps onto skin immediately after showering while skin is still damp. Focus on areas needing extra hydration like arms, legs, and knees.

3

For Hair

Rub a small amount between hands and smooth through dry or wet hair to add shine and tame flyaways, split ends, and frizz.

4

Pro Tip

Apply on damp skin for optimal absorption. Mix with your favorite moisturizer for a hydration boost, or add a drop to foundation for a dewy finish.

πŸ‘€ Who Is It For?

βœ… Perfect for you if:

  • You have dry, dehydrated, or dull skin
  • You want a simple, one-ingredient moisturizer
  • You need a pregnancy or breastfeeding safe option
  • You have fungal acne or Malassezia concerns
  • You want a multi-purpose product for face, body, and hair
  • You prefer clean, sustainable beauty products
  • You have sensitive or reactive skin
  • You want to boost other product absorption

❌ Consider alternatives if:

  • You prefer heavier, richer moisturizers
  • You want additional active ingredients like vitamin C
  • You're on a very tight budget (more affordable dupes exist)
  • You dislike oil textures entirely

🎯 Skin Type Compatibility

Oily Skin β˜…β˜…β˜…β˜…β˜… Excellent

Lightweight formula absorbs instantly without adding shine. Helps balance natural oil production rather than exacerbating it.

Dry Skin β˜…β˜…β˜…β˜…β˜… Excellent

Locks in moisture and prevents water loss. Use generously on extra-dry areas. Layer with a heavier cream in winter if needed.

Combination Skin β˜…β˜…β˜…β˜…β˜… Excellent

Adapts to different zones perfectly. Hydrates dry areas without making oily zones greasy.

Sensitive Skin β˜…β˜…β˜…β˜…β˜… Excellent

Single ingredient formula minimizes irritation risk. Hypoallergenic and dermatologist tested. Helps calm redness.

Acne-Prone Skin β˜…β˜…β˜…β˜…β˜… Excellent

Non-comedogenic and fungal acne safe. Many users report it helps clear clogged pores rather than causing breakouts.

πŸ“ˆ Results Timeline

Immediately

Instant Hydration

Skin feels instantly moisturized and soft. Absorbs within seconds without greasy residue.

95% noticed
1 Week

Softer, Smoother Texture

Skin appears softer and smoother. Rough patches begin to diminish. Makeup applies more evenly.

95% noticed
2 Weeks

Improved Nourishment

Skin feels deeply nourished and hydrated throughout the day. Visible reduction in dry flakes and tightness.

93% noticed
5 Weeks

Enhanced Cell Renewal

Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

100% clinically proven

⭐ Ratings by Platform

πŸ’„ Sephora
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
831+
Reviews
⚠️ Main complaint: Higher price point compared to competitors offering similar single-ingredient formulas
πŸ›’ Amazon
β˜…β˜…β˜…β˜…β˜… 4.6
Rating
5,000+
Reviews
⚠️ Main complaint: Pump dispenses more product than needed for face-only use
🏠 Biossance Website
β˜…β˜…β˜…β˜…β˜… 4.8
Rating
900+
Reviews
⚠️ Main complaint: Wish there was an even larger size for full-body application
✨ Influenster
β˜…β˜…β˜…β˜…β˜… 4.7
Rating
2,500+
Reviews
⚠️ Main complaint: Works so well users feel compelled to try other Biossance products (expensive habit!)

βš–οΈ Pros & Cons

βœ… Praised

  • Ultra-lightweight and fast-absorbing
  • Single pure ingredient - minimal reaction risk
  • Multi-purpose for face, body, and hair
  • Pregnancy and breastfeeding safe
  • Fungal acne safe (sugarcane source)
  • Non-comedogenic and non-greasy
  • Sustainable and cruelty-free
  • Large 100ml bottle with convenient pump
  • Works under makeup without pilling
  • Visibly calms redness and irritation

❌ Criticized

  • Higher price than The Ordinary alternative
  • Pump may dispense too much product
  • Very dry skin may need additional moisturizer
  • Minimal active benefits beyond hydration
  • No dropper option for precise application

πŸ’° Budget-Friendly Alternatives (Dupes)

95% Match
The Ordinary 100% Plant-Derived Squalane
$7.90 Budget Pick

Nearly identical single-ingredient formula. Plant-derived but source unspecified (may be olive). Dropper bottle instead of pump. Slightly thicker texture that takes a bit longer to absorb.

90% Match
Timeless Squalane Oil 100% Pure
$12.00 Budget Pick

Olive-derived squalane with excellent reviews. Medium-weight texture, great as makeup primer. Glass dropper bottle. May not be ideal for severe fungal acne concerns due to olive source.

88% Match
Good Molecules Squalane Oil
$8.00 Budget Pick

Olive-derived 100% squalane. Thicker consistency that still absorbs well. Smaller bottle size but excellent value. Fun, colorful packaging.

75% Match
Indeed Labs Squalane Facial Oil
$14.99 Similar Price

Sugarcane-derived like Biossance with ultra-light "dry oil" texture. Excellent for oily skin. Smaller bottle but clinical-grade quality with anti-aging claims.

πŸ”„ Comparison with Competitors

The Ordinary 100% Squalane

$7.90
Key Ingredient Squalane 100%
Source Plant (unspecified)
Size 30ml
Cost per oz $7.90/oz
Fungal Acne Safe Likely βœ”
Packaging Glass dropper

Timeless Squalane Oil

$12.00
Key Ingredient Squalane 100%
Source Olive
Size 60ml
Cost per oz $6.00/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

Good Molecules Squalane

$8.00
Key Ingredient Squalane 100%
Source Olive
Size 13ml
Cost per oz $18.46/oz
Fungal Acne Safe Use caution
Packaging Glass dropper

πŸ“¦ Storage & Shelf Life

πŸ“…
Period After Opening (PAO)

12 months after opening

🏠
Storage

Store in a cool, dry place away from direct sunlight. No refrigeration needed. Squalane is highly stable.

πŸ“¦
Packaging

Recyclable plastic pump bottle. Outer carton made from FSC-certified sugarcane paper.

✈️
Travel Friendly

Yes, the 100ml size meets TSA carry-on liquid requirements

❓ Frequently Asked Questions

Yes, absolutely. Biossance 100% Squalane Oil is pregnancy and breastfeeding safe. Squalane contains no retinoids, salicylic acid, hydroquinone, or any ingredients that are contraindicated during pregnancy. In fact, Biossance was named the best pregnancy-safe skincare brand by The Bump in 2024, and dermatologist Dr. Alexis Stephens specifically recommends this product for preventing stretch marks during pregnancy.

Yes. Sugarcane-derived squalane like Biossance's is considered safe for fungal acne-prone skin. Unlike olive-derived squalane which may contain trace impurities, sugarcane squalane is synthesized via bio-fermentation resulting in approximately 99% pure hydrocarbons with no fatty acids that Malassezia can metabolize. It's a saturated hydrocarbon that does not feed the yeast that causes fungal acne.

Yes! Squalane is compatible with all skincare actives including retinol, vitamin C, AHAs, BHAs, niacinamide, and peptides. In fact, squalane helps boost the absorption of other active ingredients and enables them to work more effectively. Apply your active treatments first, then seal everything in with squalane as your final step.

Biossance 100% Squalane Oil works excellently for all skin types: normal, dry, combination, oily, sensitive, and acne-prone. The lightweight, fast-absorbing formula adapts to different skin needs - it hydrates dry areas without making oily zones greasy. It's particularly loved by those with sensitive skin due to its single-ingredient formula and hypoallergenic properties.

Results are immediate and progressive. You'll notice instant hydration and softness right away. After 1 week, skin appears softer and smoother. By 2 weeks, 93% of users reported more nourished, hydrated skin. Clinical studies show 100% of subjects experienced increased cell renewal rate after 5 weeks of twice-daily use.

Apply squalane oil as your final step after cleansing, toning, serums, and moisturizer. It acts as a "seal" to lock in all your previous products. For daytime, apply before sunscreen. You can also mix a drop into your moisturizer or foundation, or apply directly to damp skin after cleansing for enhanced absorption.

No, Biossance 100% Squalane Oil is non-comedogenic with a rating of 1/5. Despite being an oil, squalane actually helps balance natural oil production rather than clog pores. Many users with acne-prone skin report that it helps clear clogged pores and reduces breakouts. The product is dermatologist tested and suitable for acne-prone skin.

The product has a 12-month (12M) Period After Opening (PAO). Squalane is highly stable and resistant to oxidation, unlike many other oils. Store in a cool, dry place away from direct sunlight. The pump bottle design also helps protect the product from air exposure and contamination.

β˜…β˜…β˜…β˜…β˜…
4.8 out of 5

Verdict: Biossance 100% Sugarcane Squalane Oil is the gold standard for pure squalane face oils. While budget alternatives like The Ordinary exist, Biossance justifies its premium with certified sugarcane sourcing (ideal for fungal acne), convenient pump packaging, and the ethical peace of mind knowing you're saving sharks. The single-ingredient formula makes it universally safe for pregnancy, sensitive skin, and virtually every skin type. If you want the purest, most sustainable squalane with clinical backing, this is the one to choose. For budget-conscious shoppers, The Ordinary offers 95% of the benefits at a fraction of the cost.